Morphological Study of The Pancreas and Duodenum in Adult Guinea Pigs (Cavia porcellus)

Abstract

The present study aimed to investigate the morphological features of the pancreas and duodenum of theadult males and females guinea pigs. Eight animals of each sex were collected to conduct this project.The selected organs were photographed in situ and macro morphometric measurements were conductedon them. Gross findings revealed that the pancreas of guinea pig was of compact type, of two lobes (rightand left) connected by large central part (body). The organ drains the pancreatic secretion toward the lastpart of the ascending duodenum via minor pancreatic duct with absence of major pancreatic duct. Theduodenum of the guinea pig was very short and V-shaped. The beginning of the duodenum containsduodenal papilla in which found central orifice for the exit of bile secretions of the common bile duct. Inconclusions, the present findings showed the presence of only one minor pancreatic duct and such resultwas significantly different than most rodents by having major pancreatic duct. The duodenum in thestudied guinea pigs was characteristically very short and V-shaped differently to other animals that haveU-shaped and long duodenum.

Abdominal ultrasound features and reference values in healthy guinea pigs (Cavia porcellus)

“…The right pancreatic lobe was not seen in any animal. This could be due to its small size relative to the left lobe, as previously reported 6 (also described in cats 26 ), or because the caecum impairs the visualisation of small abdominal structures.…”

“…The animals were placed in dorsal recumbency, the abdominal hair was clipped from the xiphoid process to the inguinal region, and tempered saline solution and gel were applied over the abdomen. Various scanning planes were used for the evaluation of different abdominal organs, which were identified based on the regional and comparative anatomy 1,4–12 of guinea pigs and rabbits 12 …”

“…According to their relationships with the adjacent digestive organs, they are called the right lobe (duodenal), body and left (splenic) lobe. 6 The major abdominal vessels, such as the aorta, caudal vena cava (CVC) and portal vein (PV) have a similar location as in dogs, cats and rabbits. 7 The CVC is located ventral and to the right of the aorta, but gradually it assumes a dorsolateral position within the lumbar and sacral regions where it receives the iliac veins from the pelvic limbs.…”

“…The pancreas is triangular and has three irregular lobes. According to their relationships with the adjacent digestive organs, they are called the right lobe (duodenal), body and left (splenic) lobe 6 . The major abdominal vessels, such as the aorta, caudal vena cava (CVC) and portal vein (PV) have a similar location as in dogs, cats and rabbits 7 .…”

Histomorphological and Histochemical Study of Esophagus and Stomach in the Neonate Guinea Pigs (Cavia porcellus)

“…T he guinea pig (Cavia porcellus) ancestor is one of the most prevalent rodents in South America. Due to their appeal as a pet and food source, they are widely spread, belong to the order Rodentia, suborder Hystricomorpha, and the Family Caviinae (Shomer et al, 2015;Al-Saffar and Nasif, 2020). Since animals consume most feed materials, they are primarily complex and insoluble.…”