Morphological substantiation of the use of laser and led irradiation in emergent treatment of ulcer complications

Abstract

The structural basis of ulcer perforation and bleeding was determined, based on morphological evaluation of gastroduodenal ulcers. The effects of low-intensive laser irradiation LILI and LED irradiation on pathomorphosis of ulcers were studied. It was found that the local phototherapy with LILI and LED increases the relative fraction volume — RFV of fibroblasts and connective tissue fibers, reduces RFV of cell-free zones, which contributes to “strengthening” of the ulcer walls and prevents their perforation. These same photo-infllead to an increase of RFV of blood vessels, indicating inappropriateness of their use for local phototherapy in bleeding ulcers.