Morphology and Chemical Purity of Water Suspension of Graphene Oxide FLAKES Aged for 14 Months in Ambient Conditions. A Preliminary Study

Abstract

Graphene and its derivatives have attracted scientists’ interest due to their exceptional properties, making them alluring candidates for multiple applications. However, still little is known about the properties of as-obtained graphene derivatives during long-term storage. The aim of this study was to check whether or not 14 months of storage time impacts graphene oxide flakes’ suspension purity. Complementary micro and nanoscale characterization techniques (SEM, AFM, EDS, FTIR, Raman spectroscopy, and elemental combustion analysis) were implemented for a detailed description of the topography and chemical properties of graphene oxide flakes. The final step was pH evaluation of as-obtained and aged samples. Our findings show that purified flakes sustained their purity over 14 months of storage.

Applicability of Atmospheric Pressure Plasma Jet (APPJ) Discharge for the Reduction in Graphene Oxide Films and Synthesis of Carbon Nanomaterials

“…The aqueous dispersion of GO was prepared with flakes obtained from graphite by a modified Hummers method. Further experimental details are described in the literature [35][36][37]. The 2 mg/mL GO dispersion in deionized water (DI) (flake size 1-100 µm) was spin-coated at 2000 rpm for 30 s on 1.5 × 1.5 cm 2 substrates.…”

Flake Graphene-Based Nanomaterial Approach for Triggering a Ferroptosis as an Attractive Theranostic Outlook for Tackling Non-Small Lung Cancer: A Mini Review

“…Understanding the specific mechanism of ferroptosis and its relationship with lung cancer could provide significant references regarding cancer therapy [ 22 , 23 , 24 ]. It is well accepted that the occurrence of ferroptosis is iron-dependent and it can be assumed that, i.e., thoughtfully designed graphene oxide [ 25 , 26 ] (very promising 2D carbon-based materials for possible biomedical application) modifications with iron can be used as a new system to induce ferroptosis. Such tailor-made graphene oxide-Fe (graphene oxide-iron) composite could be a good option to induce and further study not only ferroptosis but other molecular changes in cancer cells after extracellular Fe intake.…”

“…This parameter should be considered regarding the design and production of high quality flake graphene-based material tailored for some strictly defined, cutting-edge anti-cancer therapies. Without the estimation of long-term stability of GO flakes [ 26 ] and GO-based covering layers, the durability and usability of any novel GO-based biomedical tool will be secreted, which in turn will greatly impede its possible biomedical application. Having this in mind, it can be assumed that, the toxicity of graphene-based materials can be different from currently reported short-term exposure results.…”

Opportunities Offered by Graphene Nanoparticles for MicroRNAs Delivery for Amyotrophic Lateral Sclerosis Treatment

“…The interaction of GBMs with neurons and astrocytes is still poorly investigated and unclear, due to the variable methods for GBM production that influence the oxygen content, lateral size, contaminants, and number of layers [ 155 ]. In one of the earlier studies, Defterali et al using rGO showed good neuronal and glial biocompatibility [ 156 , 157 ].…”