Morphology and immunohistochemistry of a symptomatic septum pellucidum cavum Vergae cyst in man

Abstract

The cavum septi pellucidi (CSP) and cavum Vergae (CV) are persistent, primitive, or acquired, midline structures of adult human brain. It is customary to distinguish between the non-communicating and the communicating cava, depending on whether the cavum communicates with the cerebral ventricular system or not. Only a few cases of symptomatic non-communicating cava, called septum pellucidum and cavum Vergae cysts, have been described in the literature. In this study, the authors describe the morphological, histological and histo-immunological characteristics of an additional case of septum pellucidum-cavum Vergae cyst in a forty-year-old man who died the day following a ventriculo-peritoneal shunt. We have found a communication between the CSP and the leptomeningeal space of the anterior interhemispheric fissure, in the absence of subarachnoid haemorrhage. The authors discuss the origin of the intracystic fluid and the classification of the CSP.

Neuroendoscopic Management of Symptomatic Septum Pellucidum Cavum Vergae Cyst Using a High-Definition Flexible Endoscopic System -Case Report-

“…7,19,20) In contrast, non-communicating cyst, which could originally be asymptomatic, 18) may enlarge, block the foramen of Monro, and cause symptomatic The check valve phenomenon between the cyst and the subarachnoid cavity may be implicated based on immunohistochemical analysis. 17) The involvement of minor head injury was also implicated in the expansion of CSP. 13) These mechanisms are based on the idea that enlargement occurs in the natural history of the cyst.…”

An Analysis of Outcome of Endoscopic Fenestration of Cavum Septum Pellucidum Cyst - More Grey than Black and White?

“…The prevalence of CSP has been reported to range from 0.14 to 18.9% in adults, whereas CV is rarer (0.134%) [2] . The radiological prevalence of CSP by adulthood in a normal individual ranges from 4 to 74% [13][14][15] .…”

“…They are actually fluid-filled, generally communicating midline cavities located between the third ventricle and corpus callosum [2,3,5] .…”

“…Purpose: To assess the surgical outcome of fenestration of a CSP cyst. Methods: Retrospective analysis of 3 patients who underwent endoscopic fenestration for CSP with obstructive hydrocephalus between 2012 and 2014 was in adult brains because of their involution early in the course of adult life [2] . The prevalence of CSP has been reported to be 0.14-18.9% in adults, whereas CV is rarer (0.134%) [2] .…”

“…Cavum septum pellucidum (CSP) and cavum vergae (CV) were formerly called the fifth and sixth ventricles of the brain [1][2][3] , but this nomenclature was later abandoned because of the absence of ependymal lining and choroid plexus in these structures [2][3][4] . They are actually fluid-filled, generally communicating midline cavities located between the third ventricle and corpus callosum [2,3,5] .…”