Morphology and Tensile Properties of Pva/Snail Mucin Nanofiber Membranes

Abstract

MORPHOLOGY AND TENSILE PROPERTIES OF PVA/SNAIL MUCIN NANOFIBER MEMBRANES. Snail mucin has been widely known to contain agents with wound healing properties. A preliminary research with regard to the potential to manufacture composite nanofibrous membranes of polyvinyl alcohol (PVA) and snail mucin (SM) by the electrospinning technique for wound dressing applications has been conducted. The effect of SM concentration on the morphology and tensile properties of PVA/SM nano membrane has been investigated. The PVA/SM solutions with various concentration of SM (0%, 2%, 4%, dan 6%)(w/v) were electrospun at the optimized process parameters. The morphology nanofiber membranes was observed by scanning electron microscopy and the average diameters of prepared nanofibers was determined by image analysis technique. The tensile test was conducted to examine the tensile properties of the nanofiber membranes being prepared according to ASTM D882. The PVA/SM nanofibre membrane possessing the tensile strength and tensile strain ranging between 3.48-5.37 MPa and 101.25-157.13 %, respectively were successfully fabricated. The membrane of 10% (w/v) PVA/ 2% (w/v) SM achieved the highest values of tensile strength. This phenomenon has been associated to the uniformity of fiber size diameter distribution within the membranes. It was expected that further optimization of the processing would allow development of the tensile properties compatibility requirement with this being the subject of future work by the authors.

Enhancing surface morphology, mechanical, and wettability properties of PVA/chitosan/HAp nanofiber scaffold through dielectric barrier discharge plasma treatment

“…This aligns with previous research by [55], which reported a positive correlation between smaller fiber diameter and higher tensile strength. The increased packing density of thinner fibers creates a more robust structure capable of withstanding greater loads [56]. This aligns with the findings from Hartatiek et al [57], who observed a similar inverse relationship between fiber diameter and mechanical properties.…”

The Fabrication and Characterization of Electrospun PVA-Snail Mucin Nanofiber Membrane

“…Overall, the diameter of the membranes fabricated in this study is comparable to that of the previous studies [20,21], which is in the range of 100-300 nm. It has been reported elsewhere that PVA-SM concentration 0% produced a membrane with fiber diameter, tensile strength, and elastic modulus of 460.17 ± 128.32 nm, 3,48 MPa, and 12.00 MPa, respectively [22].…”

“…The tensile testing procedure was prepared in accordance with ASTM D882. The prepared specimen [22] was depicted in Figure 2.…”

“…The concentration of aqueous PVA solution chosen in this work was at 10% (w/v) due to its capability to produce nanofiber as reported elsewhere [22]. Even though the parameters are important, conductivity and viscosity of polymer are the most significant parameters influencing the final characteristic of the electrospun fiber [5].…”

“…However, those investigates have not reported their mechanical properties. Nugroho et al, [22] have successfully manufactured the PVA-SM nanofiber membrane bead-free utilizing the electrospinning method with fiber size diameter in the range of 200-900 nanometer. The addition of SM into the polymer solution influences the fiber morphology leading to affect mechanical properties of the membrane.…”