Morphology of cerebral lesions in children with congenital hemiplegia

Wiklund, Lars‐Martin; Uvebrant, Paul; Flodmark, Olof

doi:10.1007/bf00589107

Cited by 60 publications

(56 citation statements)

References 52 publications

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“…Studies conducted by Wiklund et al 17 showed that 17% of the CP-H cases had CNS-MF. Some reports give great importance to the presence of physical malformations outside the CNS because they indicate the occurrence of a lesion and therefore the period can be defined 1,3,4,11 .…”

Section: Discussionmentioning

confidence: 98%

“…Although great progress has been achieved in relation to imaging in CP-H, 8% to 24% of the exams are reported as normal 15,17,21 . In the present study, the CT exam was normal in 18% of the cases and the MRI in 7% of the cases, demonstrating that MRI is a more efficient tool in the neroimaging evaluation of PC-H.…”

Section: Discussionmentioning

confidence: 99%

“…In cases of CP-H which occur in full term infants, the most common finding is a lesion in the area of the middle cerebral artery mainly the left one and this factor is not described for the other types of CP 6,15,17,19 . Ischemic lesion in the parasagital white matter is generally related to hypoxic ischemic encephalopathy (HIE) or prolonged hypoxy which results in subcortical leukomalacia with a reduction in the white mater and ex-vacuum ventricular enlargement resulting in hemispheric atrophy 7 .…”

mentioning

confidence: 98%

“…The premature infants present unstable cardiac and respiratory regularity which lead to cerebral hypoperfusion and consequently PVL or periventricular hemorrhagic infarct, both of which are commonly found in CP-H [11][12][13][14][15] . Hypodense areas are common in FTI, mainly in the watershed areas, and probably represent areas of perfusional failure [15][16][17][18] .…”

mentioning

confidence: 99%

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Hemiparetic cerebral palsy: etiological risk factors and neuroimaging

Piovesana

Moura-Ribeiro

Zanardi

et al. 2001

Arq. Neuro-Psiquiatr.

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-The purpose of this paper, which was conducted on 175 children with hemiparetic cerebral palsy (H-CP), was to verify the etiological risk period for this disease. Etiological risk factors (ERF) were detected through anamnesis: 23% in the prenatal period, 18% in the perinatal period and 59% of the patients the period was undefined (ERF in the prenatal and perinatal period was 41% and no ERF was 18% of the cases. The computerized tomographic scan (CT) and MRI were performed on all the patients, who were then classified according to their etiopathogenic data: CT1= normal (18%); CT 2= unilateral ventricular enlargement (25%); CT 3= cortical/ subcortical cavities (28%); CT4= hemispheric atrophy and other findings (14%); CT 5= malformations (15%). CT 5 was associated with physical malformations beyond the central nervous system and with prenatal ERF s , while CT 2 was associated with the perinatal ERF s, mainly in premature births. Magnetic resonance imaging was performed on 57 patients and demonstrated a good degree of concordance with the CT. Etiology remained undefined in only 37% of the cases after neuroimaging was related to ERF. A high perinatal RF frequency (59%) was observed and emphasized the need for special care during this period.KEY WORDS: cerebral palsy, hemiparetic cerebral palsy, etiology, etiological risk factors, computerized tomography, magnetic resonance imaging, children.Paralisia cerebral hemiparética: fatores de risco etiológico e neuroimagem RESUMO Foram estudadas 175 crianças com paralisia cerebral hemiparética (PC-H) para elucidar o período de risco etiológico. Através da anamnese constataram-se fatores de risco para etiologia (FRE) pré-natal em 23%, perinatal em18% e período indefinido em 59% dos pacientes (com FRE pré e perinatal 41% e sem FRE 18%). A tomografia computadorizada (TC) foi realizada em todos os sujeitos e classificada de acordo com dados etiopatogênicos em: TC1= normal (18%); TC2= alargamento ventricular unilateral (25%); TC3= cavidades córtico-subcorticais (28%); TC4= atrofia hemisférica e outros achados (14%); TC5= malformações (15%). A TC5 se associada a malformações físicas fora do sistema nervoso central e aos FRE pré-natais e a TC2 aos perinatais, principalmente, nascer prematuro. A ressonância magnética foi realizada em 57 sujeitos demonstrando boa concordância com a TC. Após associação da neuroimagem e FRE a etiologia ficou indefinida em apenas 37%. Constatou-se alta frequência de FRE perinatais (59%), alertando para melhores cuidados neste período. PALAVRAS-CHAVE: paralisia cerebral, paralisia cerebral hemiparética, etiologia, fatores de risco, tomografia axial computadorizada, ressonância magnética, crianças Despite the recent improvement in maternal infantile health care, cerebral palsy (CP) and its mechanisms are still not fully understood. The incidence of this disease, in its moderate and serious forms is around 2.5:1000 live births 1 . CP is defined as a non progressive motor disorder which is secondary to a lesion of an immature brain and includes abn...

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 98%

mentioning

confidence: 99%

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Hemiparetic cerebral palsy: etiological risk factors and neuroimaging

Piovesana

Moura-Ribeiro

Zanardi

et al. 2001

Arq. Neuro-Psiquiatr.

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“…Although MRI is known to display a greater sensitivity, 22 CT is considered an adequate imaging modality for corticalsubcortical lesions in the territory of the middle cerebral artery. 23 As such, these imaging data were retained. Patients' age at the time of the scan ranged from 5 days to 15 years with a mean of 5 years 7 months (SD 4 years 6 months).…”

Section: 2mentioning

confidence: 99%