Morphometric Assessment of Human Corpus Callosum on Cadaveric Brain Specimens

Abstract

BACKGROUND Corpus callosum is the main commissural tract between the two halves of the brain and assumes an essential job in transferring sensory, motor, and cognitive data from identical regions in the two brain hemispheres. Literature on the issue of the human corpus callosum sexual dimorphism is not universal. Similarly, age related change in corpus callosum measurements is also not consistent. METHODS Different diameters of brain and corpus callosum like longitudinal and vertical diameters of brain and length, height, widths of corpus callosum etc. were measured with digital vernier caliper. RESULTS 37 brains were collected, out of which 24 were male & 13 were female brains of various ages between 20 years and 70 years of age. Average longitudinal & vertical diameters of brain specimens under study were 158.29 mm and 102.41 mm respectively and average length of corpus callosum was 72.19 mm. Change in length of corpus callosum in relation to gender is not significant with p value >0.05. There is decrease in length of corpus callosum after 65 years of age. CONCLUSIONS Positive linear correlation was observed between length of corpus callosum and the length & vertical diameters of brain. The study has failed to establish statistically significant gender differentiation in the diameters of corpus callosum. Also, there was decrease in the length of corpus callosum (EZ) in 65 years and above age group with decrease in height and width of body as well as splenium of corpus callosum between 50-60 years age group.

Morphometry of Corpus Callosum in South Indian Population

“…Figure 3. Comparison of LC (cm) from Present Study and Values Reported from Other Studies (** Indicates MRI Study) 14,22,17,18,23. …”