Mortalidad después del trasplante de riñón: resultados a 10 años

Abstract

Objectives: In the past decade, advances in immunological therapy have increased the survival of kidney recipients and their grafts. However, it has not achieved the desired level of improvement. This study aims to reveal the mortality among kidney recipients. Methods: Medical data of the patients, who had undergone kidney transplantation (KT) between November 2010 and December 2020, were retrospectively reviewed. Inclusion criteria were adult kidney recipients, who had died. Exclusion criteria were pediatric recipients, recipients of en bloc and dual KT, recipients with missing data, and recipients with a primary non-functioning graft. The recipients were grouped according to their donor type; Group 1 (from a living donor) and Group 2 (from a deceased donor). Subgroup analyses were done for mortality by time-period post-transplant and for infectious causes of mortality. Results: Of 314 recipients, 35 (11.14%) died. Twenty-nine recipients were included in the study (Group 1: 17 and Group 2: 12). The most common cause of mortality was infection (58.6%), and the second was cardiovascular disease (CVD) (24.1%). Sepsis developed in 29.4% of infection-related deaths, while COVID-19 constituted 23.5% of infection-related deaths. Conclusion:Early diagnosis and treatment of infectious and CVD are important to improve survival in kidney recipients.

Moderator Effect of Transplant Waiting Time on the Relationship Between Hopelessness and Death Anxiety in Patients Waiting for Organ Transplant

“…In the study conducted by Kainz et al, patients waited five years until the first transplantation (Kainz et al, 2022). In the study of Piskin et al, it was reported that patients waited 6 years (74 months) for organ transplantation (Piskin et al, 2022). In our study, it was observed that the waiting time was lower than in the literature, leastwise.…”

Endotoxin and Cytokines Removal with Adsorption Device in a Child with Sepsis After Transplantectomy (Case Report)

“…По данным исследования T. Piskin и соавт., в первые 2 мес. после трансплантации почки, когда наиболее интенсивно применялась иммуносупрессия, инфекция была единственной первопричиной летальности [9].…”