BackgroundBlunt trauma is a potentially life-threatening injury that requires prompt diagnostic examination and therapeutic intervention. Nevertheless, how impactful a rapid response time is on mortality or functional outcomes has not been well investigated. This study aimed to evaluate effects of earlier door-to-computed tomography time (D2CT) and door-to-bleeding control time (D2BC) on clinical outcomes in severe blunt trauma.MethodThis was a single-center, retrospective cohort study of patients with severe blunt trauma (Injury Severity Score > 16) treated between August 2007 and July 2015 in a tertiary trauma center in Japan. Patients who underwent whole-body CT scanning within 90 minutes of emergency room arrival were included. To assess the effect of earlier D2CT and D2BC on 28-day mortality, we conducted multivariable regression analyses with consideration of non-linear associations. The effects on 24-hour mortality and the Oxford Handicap Scale were also evaluated as secondary outcomes.ResultsAmong 671 patients with severe blunt trauma who underwent CT scanning, 163 patients received an emergency bleeding control procedure. The median D2CT and D2BC were 19 min (IQR 12–27) and 57 min (IQR 45–75), respectively. In a Cox proportional hazard regression model, earlier D2CT was not associated with improved 28-day mortality (p = 0.30), whereas earlier D2BC was significantly associated with improved 28-day mortality (p = 0.026). This beneficial trend of D2BC was consistently observed for the assessment of secondary outcomes.ConclusionAmong patients with severe blunt trauma undergoing CT scanning, time benefits were not observed for the CT examination itself but were for therapeutic bleeding control.