Mortality & COVID-19: A Snapshot of a Tertiary Care Facility in Pakistan

Abstract

Introduction: Ever since Sars CoV-2 infection has started from China and has taken the shape of pandemic the mortality associated with this disease has been under discussion and hypercoagubility, acute severe respiratory syndrome and sepsis with multi organ failure have been accursed as possible reasons of deaths in cases infected with novel Corona virus. We conducted a retrospective analysis of the cases admitted in our high dependency and Intensive care unit and tried to pinpoint the major cause of mortality in our cases. Methods: This is a single center retrospective study carried out at Bahria International Hospital Lahore over a 3 month period (May 10th to July 10th 2020) in which we analyzed the clinical and biochemical profiles of the COVID-19 patients who died during this period. Results: A total of 108 patients were admitted during this period out of which 11 patients died. 7 of them were men and 4 women. Majority of them had sudden cardiac arrest due to acute coronary syndrome followed by multiorgan dysfunction syndrome and acute respiratory distress syndrome. Conclusion: Acute coronary syndrome due to hypercoagubility was the leading cause of death in our patients.

Assessment of Predictors of Mortality in COVID-19 Patients Treated with Tocilizumab

“…Tocilizumab and sarilumab, two immunosuppressive IL-6 inhibitors, have been demonstrated to reduce mortality in critically ill patients, including those on ventilators, by 8.5%. Furthermore, it is still unknown what factors led to a favourable tocilizumab response in COVID-19 9,10 . Asians have a high incidence of sickness and are prone to illness.…”