Mortality and neurodevelopmental outcome at 1 year of age comparing hybrid and Norwood procedures

Knirsch, Walter; Liamlahi, Rabia; Hug, Maja I.; Hoop, Ricarda; Rhein, Michael von; Prêtre, René; Kretschmar, Oliver; Latal, Beatrice

doi:10.1093/ejcts/ezr286

Cited by 61 publications

(62 citation statements)

References 19 publications

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“…The question remains if the Hybrid technique will yield similar results. Only one study to date has reported neurodevelopmental outcomes in this cohort of HLHS patients following Hybrid Stage I palliation compared to the traditional Norwood procedure [16]. Results showed no significant difference in 1 year mortality.…”

Section: Discussionmentioning

confidence: 84%

Early Results of Neurodevelopment Following Hybrid Stage I for Hypoplastic Left Heart Syndrome

et al. 2014

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Motor skills and neurodevelopment in infants with hypoplastic left heart syndrome (HLHS) who have undergone Hybrid Stage I palliation is unknown. The purpose of this study is to assess early neurodevelopment in infants with HLHS after Hybrid Stage I palliation. Developmental assessment was performed in HLHS infants who underwent Hybrid Stage I palliation at 2 and 4 months of age using the Test of Infant Motor Performance, and at 6 months of age, prior to undergoing the second staged surgery, using the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III). Results were compared to healthy control subjects and norm-referenced data. The HLHS group scored between -1 and -2 standard deviations (SD) below the mean at 2 months of age (p = 0.002), and within -1 SD of the mean, at 4 months of age (p = 0.0019), on the TIMP. Compared to the control group, composite motor skills were significantly lower at 6 months of age on the Bayley-III in the HLHS group (p = 0.0489), however, not significant for cognitive (p = 0.29) or language (p = 0.68). Percentile rank motor scores were 17 ± 20 % in the HLHS group compared to 85 ± 12 % for the healthy age-matched control group. Infants with HLHS who undergo Hybrid Stage I palliation score lower on standardized motor skill tests compared to healthy age-matched controls and the norm-referenced population. This suggests that infants with HLHS have poorer motor skill performance than typically developing infants at 6 months of age.

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Section: Discussionmentioning

confidence: 84%

Early Results of Neurodevelopment Following Hybrid Stage I for Hypoplastic Left Heart Syndrome

et al. 2014

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“…Data comparing neurodevelopmental outcomes, one of the main potential theoretical advantages of the hybrid procedure, are only just starting to emerge. Knirsch et al analysed neuromotor scores at 3 and 12 months in 31 patients (Hybrid 13, NW 18) [1]. Neurodevelopmental outcome was significantly lower overall in patients with hypoplastic left heart syndrome compared with normal, with no significant difference between Norwood 1 and hybrid groups.…”

Section: Catheter Interventional Track Overviewmentioning

confidence: 99%

Highlights of the 6th World Congress in Paediatric Cardiology and Cardiac Surgery

et al. 2013

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The 6th World Congress in Paediatric Cardiology and Cardiac Surgery took place in Cape Town, South Africa, in February 2013. The congress is the largest meeting in the field of congenital and paediatric heart disease and attracts a global audience of specialists with the aim of sharing the latest multidisciplinary developments in research and clinical practice. The congress was commended as a huge success and this article aims to give a general flavor of the diverse meeting through detailing a few specific highlights from the various tracks.

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“…Neonatal cardiopulmonary bypass can cause brain injury, which can result in severely impaired motor and cognitive neurodevelopmental outcomes, although notable advances and innovations have been made in cardiopulmonary bypass, surgical techniques, and instruments [3,4]. Moreover, patients with severe coronary heart disease (CHD) have significantly impaired early neurodevelopmental outcomes, although the mortality rate after a hybrid procedure is similar to that after the Norwood procedure [5].…”

Section: Introductionmentioning

confidence: 99%

Usefulness of Percutaneous Transluminal Pulmonary Artery Balloon Angioplasty after Bilateral Pulmonary Artery Banding: Prevention against Additional Surgical Interventions

Ishii¹,

Miyamoto²,

Nakajima³

et al. 2017

Interv Cardiol J

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Objectives: We evaluated the efficacy of balloon dilatation after bilateral pulmonary artery banding for the treatment of severe congenital heart disease that depends on patent ductus arteriosus for systemic circulation.Background: Neonatal cardiopulmonary bypass can cause brain injury, which may result in a severely impaired neurodevelopmental outcome. Hence, we perform bilateral pulmonary artery banding combined with postoperative percutaneous trans catheter angioplasty with balloon dilatation as first-stage palliation.

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Mortality and neurodevelopmental outcome at 1 year of age comparing hybrid and Norwood procedures

Cited by 61 publications

References 19 publications

Early Results of Neurodevelopment Following Hybrid Stage I for Hypoplastic Left Heart Syndrome

Early Results of Neurodevelopment Following Hybrid Stage I for Hypoplastic Left Heart Syndrome

Highlights of the 6th World Congress in Paediatric Cardiology and Cardiac Surgery

Usefulness of Percutaneous Transluminal Pulmonary Artery Balloon Angioplasty after Bilateral Pulmonary Artery Banding: Prevention against Additional Surgical Interventions

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