Mortality From Myocardial Infarction in Russia in the Years 2006 and 2015

Самородская, И. В.; Барбараш, О. Л.; Кашталап, В. В.; Старинская, М. А.

doi:10.15829/1560-4071-2017-11-22-26

Cited by 22 publications

(10 citation statements)

References 6 publications

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“…Одним из таких факторов, несмотря на существующие правила ВОЗ для определения первоначальной причины смерти, является методически разный подход к определению первоначальной причины смерти и некорректный учет причин смерти. В России существуют определенные проблемы с интерпретацией терминов острых форм ИБС, диагностикой и кодированием их в статистических документах, что может влиять на показатели смертности [7].…”

Section: Discussionunclassified

Changes in mortality rates from acute types of coronary artery disease in Russia for the period from 2015 to 2019

Драпкина¹,

Бубнова²,

Самородская³

et al. 2021

Russ J Cardiol

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Aim. To identify regional specifics of changes in mortality rates from acute types of coronary artery disease (CAD) in 82 Russian regions for the period from 2015 to 2019.Material and methods. The study used data from the Federal State Statistics Service of Russia on mortality from acute CAD types in 82 Russian regions. Standardized death rates (SDRs) for 2015 and 2019 were estimated based on the European standard. We analyzed the SDRs of the population from acute (primary) and recurrent myocardial infarction (MI), other acute CAD types (I21-I22, I24.8 in the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10)).Results. Over the period from 2015 to 2019, mortality from all acute CAD types decreased by 21%, from acute MI — by 9%, from recurrent MI — by 22%, from any MI (acute/recurrent) recurrent — by 14%, and from other CAD types — by 21%. A decrease in mortality from all acute CAD types was recorded in 69 regions, from acute MI — in 58 regions, and recurrent MI — in 62 regions. However, a simultaneous decrease in SDRs from each of the acute CAD types (acute MI, recurrent MI and other acute CAD types) for the period 2015-2019 occurred only in 29 Russian regions. An increase in mortality from all acute CAD types was noted in 14 regions and from any MI — in 21 regions. The coefficient of variation (Cv) for recurrent MI and other acute CAD types of 69% and 103%, respectively, in 2015 and its growth (up to 75% and 134%, respectively) by 2019 indicate growing problems with the coding of death causes.Conclusion. In 2019, compared to 2015, a decrease in mortality from acute CAD types was recorded in most Russian regions. The identified regional specifics require clarification of approaches to death cause coding and the introduction of additions to mortality reduction programs, taking into account the specifics of each Russian region.

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Section: Discussionunclassified

Changes in mortality rates from acute types of coronary artery disease in Russia for the period from 2015 to 2019

Драпкина¹,

Бубнова²,

Самородская³

et al. 2021

Russ J Cardiol

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“…Результаты проведенного исследования демонстрируют лидирующие позиции сердечно-сосудистой патологии и онкологических заболеваний среди основных причин летальности. Полученные данные полностью соответствуют структуре причин смертности как в Российской Федерации [1], так и в экономически развитых странах в целом [17]. Среди фатальных сердечно-сосудистых осложнений первое место по итогам исследования занимает ИМ, летальность при котором составила 22,87 %, что также сопоставимо со структурой причин смертности в Российской Федерации [1,18].…”

Section: Discussionunclassified

“…При этом 25,5 % случаев фатальных ИМ 2-го типа приходятся на пациентов хирургического профиля. Н есмотря на быстрые темпы развития современной медицинской науки, появление новых высокотехнологичных методов диагностики и лечения в кардиологии, смертность от заболеваний сердечно-сосудистой системы и, в частности от инфаркта миокарда (ИМ), по-прежнему остается довольно высокой [1]. С учетом гетерогенности ИМ, выражающейся в различиях патогенеза и клинических проявлений, определяемых непосредственной причиной развития некроза сердечной мышцы [2], в 2007 г. впервые была предложена клиническая классификация ИМ [3], согласно которой в настоящее время выделяют 5 типов ИМ [4].…”

Section: заключениеunclassified

The Frequency of Type 2 Myocardial Infarction in the Structure of Hospital Mortality According to 7-Years Data of a State University Clinic

et al. 2020

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Aim To evaluate the proportion of type 2 myocardial infarction (MI) in the structure of mortality at a multidisciplinary hospital; to describe major causes for MI development, and characteristics of patients with a verified diagnosis of type 2 MI by data of postmortem examination.Material and methods 1574 protocols of the autopsies performed at the Central Pathology Department of the I.I. Mechnikov North-West State Medical University from 01.01.10 through 31.12.16 were studied retrospectively by the continuous sampling method. A group with verified diagnosis of type 2 MI was isolated from the total sample of autopsies. Major causes for and the proportion of type 2 MI among the causes of death were studied. Also, major demographic parameters, hospitalization profile, and condition of coronary arteries (CA) were compared in patients with fatal type 2 MI and those who died from atherothrombotic type 1 MI.Results Analysis of 1574 fatal cases among patients of the multidisciplinary hospital showed that in 360 cases (22.87 %), the cause of death was MI, including 137 cases of fatal type 2 MI. Proportions of men and women among the patients with postmortem verification of type 2 MI were comparable. Analysis of the age structure showed the highest incidence of type 2 MI in elderly (48.2 %) and senile (34.3 %) age. Mean age of patients with type 2 MI was 71.7 years (68.2 years for men and 75.3 years for women), which was comparable with the age range of patients with fatal type 1 MI. In both groups, men with fatal MI were significantly younger than women. Analysis of causes for type 2 MI demonstrated that the most frequent ones were tachysystolic arrhythmias (59.12 %) and severe hypoxia of different origin (35.04 %). Analysis of the type of CA lesions showed that significant lesions were significantly more frequently absent in type 2 MI (32.85 %) while in type 1 MI, the proportion of patients with unchanged CA was 1.84 %. In the group of patients with fatal type 1 MI, 67.29 % had multivascular lesions, and one in two patients had an occlusive lesion. In the group with type 2 MI, multivascular lesions were half as frequent (31.38 %), and only 4.38 % of patients had a complete occlusion of a coronary vessel. Comparison of death rate in different departments of the multidisciplinary hospital showed that only 29.2 % of patients with type 2 MI originally were managed at a specialized cardiological department; 45.3 % of patients were admitted to an internal medicine department for different conditions often not related with ischemic heart disease. Furthermore, 25.5 % of patients with subsequently developed type 2 MI originally even received scheduled or emergency medical care for a leading surgical condition.Conclusion Cardiovascular diseases predominate among causes of mortality in a multidisciplinary hospital. This study showed that almost one in four patients dies from MI, and type 2 MI accounts for more than one third of fatal MIs. Among major causes for type 2 MI, tachysystolic arrhythmias (59.12 %) and pronounced hypoxia associated with anemia and severe respiratory failure (35.04 %) should be noted. Gender and age characteristics of patients with type 2 MI were comparable with those of patients with fatal type 1 MI. Furthermore, surgical patients accounted for 25.5 % of fatal cases of type 2 MI.

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“…На протяжении многих десятилетий заболевания сердечно-сосудистой системы (ССС) являются одной из основных причин инвалидизации и высокой смертности трудоспособного населения [1][2][3]. Неутешительным является и тот факт, что заболеваемость инфарктом миокарда с подъёмом сегмента ST (ИМпST) демонстрирует свой рост среди молодого, чаще мужского, населения [4][5][6]. Развитие хронической сердечной недостаточности (ХСН), как наиболее часто встречающегося позднего осложнения инфаркта миокарда (ИМ), все чаще прогрессирует на фоне сохраненной сократительной способности миокарда [7].…”

Section: In-hospital Changes Of Echocardiographic Parameters and Theiunclassified

In-hospital changes of echocardiographic parameters and their relationship with the procollagen I C-terminal propeptide in patients with myocardial infarction and preserved left ventricle systolic function

Осокина¹,

Каретникова²,

Поликутина³

et al. 2020

Russ J Cardiol

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Aim. To study the changes of echocardiographic parameters and their relationship with the procollagen I C-terminal propeptide (PICP) during hospitalization of patients with ST-segment elevation myocardial infarction (STEMI) and preserved left ventricular (LV) systolic function.Material and methods. A total of 120 (100%) patients hospitalized with STEMI were examined. Upon admission, all patients underwent standard examinations to verify myocardial infarction (MI), including coronary angiography and, if necessary, coronary stent implantation. The mean values of LV ejection fraction (LVEF) were 40-49% in 3 patients (2,5%), <40% — in 31 patients (26%), LVEF was. We also analyzed patients with LVEF ≥50%, n=86 (71,6%); mean age was 57,8 years. During the hospitalization, all patients received standard therapy; on the 1st and 12th day of MI, the PICP levels in venous blood serum was determined by enzyme-linked immunosorbent assay. In order to compare PICP values, a control group of healthy volunteers n=20 (100%) was formed, which were comparable by gender and age. In this group, the concentration of PICP was 179,2 [163.5; 194.9] ng/ml.Results. By the 12th day, a significant decrease in the following parameters of the transmitral flow was revealed: DT (p=0,049), dE (0,012), Em (0,029), Em/ Am (p=0,000), Em/PICP (p=0,001). This indicates diastolic function deterioration. At the same time, by the end of hospitalization, systolic function deterioration was recorded in 15,1% of cases. Initially, a higher PICP on the 1st day relative to the control group tended to decrease the concentration by the 12th day, but the differences did not reach statistical significance (p=0,466). Correlation analysis showed a relationship between PICP and echocardiography (Tei index, p=0,026, and mitral annulus velocity, p=0,049).Conclusion. At the hospital stage of treatment of patients with STEMI and preserved LVEF, a negative changes of echocardiography parameters characterizing diastolic dysfunction was revealed. Positive correlation was established between the concentration of PICP with mitral annulus velocity and the Tei index, indicating an association between the myocardial fibrosis and diastolic dysfunction.

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Mortality From Myocardial Infarction in Russia in the Years 2006 and 2015

Cited by 22 publications

References 6 publications

Changes in mortality rates from acute types of coronary artery disease in Russia for the period from 2015 to 2019

Changes in mortality rates from acute types of coronary artery disease in Russia for the period from 2015 to 2019

The Frequency of Type 2 Myocardial Infarction in the Structure of Hospital Mortality According to 7-Years Data of a State University Clinic

In-hospital changes of echocardiographic parameters and their relationship with the procollagen I C-terminal propeptide in patients with myocardial infarction and preserved left ventricle systolic function

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