Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum

Giadinis, Nektarios D.; Petridou, Evanthia; Sofianidis, George; Filioussis, George; Psychas, V.; Hatzopoulou, E; Karatzias, H.

doi:10.1136/vr.163.9.278

Cited by 18 publications

(12 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Long acting oxytetracycline has prevented disease and deaths and also controlled CCPP outbreak (Giadinis et al. 2008). Tiamulin was considered as one of the treatments of CCPP (Aytug et al.…”

Section: Treatmentmentioning

confidence: 99%

Contagious caprine pleuropneumonia – a comprehensive review

Yatoo

Parray

Bashir

et al. 2019

Veterinary Quarterly

View full text Add to dashboard Cite

Contagious caprine pleuropneumonia (CCPP) is a serious disease of goats, occasionally sheep and wild ruminants, caused by Mycoplasma capricolum subspecies capripneumoniae (Mccp). The disease is characterized by severe serofibrinous pleuropneumonia, very high morbidity ($100%), and mortality (80-100%). CCPP affects goats in more than 40 countries of the world thereby posing a serious threat to goat farming around the globe. The characteristic clinical signs of CCPP are severe respiratory distress associated with sero-mucoid nasal discharge, coughing, dyspnea, pyrexia, pleurodynia, and general malaise. In later stages, severe lobar fibrinous pleuropneumonia, profuse fluid accumulation in pleural cavity, severe congestion of lungs and adhesion formation is observed. Mycoplasmal antigen interactions with host immune system and its role in CCPP pathogenesis are not clearly understood. CCPP is not a zoonotic disease. Diagnosis has overcome cumbersome and lengthy conventional tests involving culture, isolation, and identification by advanced serological (LAT, cELISA) or gene-based amplification of DNA (PCR, RFLP, and hybridization) and sequencing. The latex agglutination test (LAT) is rapid, simple, and better test for field and real-time diagnosis applicable to whole blood or serum and is more sensitive than the CFT and easier than the cELISA. Moreover, the studies on antibiotic sensitivity and exploration of novel antibiotics (fluoroquinolones, macrolides) can help in better therapeutic management besides preventing menace of antibiotic resistance. Re-visiting conventional prophylactic measures focussing on developing novel strain-based or recombinant vaccines using specific antigens (capsular or cellular) should be the most important strategy for controlling the disease worldwide.

show abstract

Section: Treatmentmentioning

confidence: 99%

Contagious caprine pleuropneumonia – a comprehensive review

Yatoo

Parray

Bashir

et al. 2019

Veterinary Quarterly

View full text Add to dashboard Cite

show abstract

“…In one case report, streptomycin-treated goats suffering from natural and experimental CCPP recovered on the third day of treatment and became completely immune to reinfection with Mccp (Rurangirwa and McGuire 2012). An administration of long acting oxytetracycline stopped morbidity and mortality, and controlled further CCPP spread immediately (Giadinis et al 2008). Danofloxacin was found to be highly effective in the treatment of clinical CCPP in goats Ozdemir et al 2006).…”

Section: Treatment and Prophylaxismentioning

confidence: 95%

Contagious caprine pleuropneumonia and its current picture in Pakistan: a review

Samiullah¹

2013

Vet. Med. - Czech

View full text Add to dashboard Cite

Contagious caprine pleuropneumonia (CCPP) is caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp) which belongs to the Mycoplasma mycoides cluster, a group of five closely related Mycoplasmas, pathogenic to ruminants. The true lesions of CCPP are restricted to the alveolar tissues of infected goats, which distinguish it from other respiratory diseases of small ruminants caused by members of the Mycoplasma mycoides cluster. The typical signs of CCPP are an accumulation of pleural fluid, unilateral hepatisation, adhesions, pleurisy and pleuropneumonia which clearly differentiate it from "MAKePS" syndrome caused by Mycoplasma mycoides subsp. capri (Mmc). The available literature on CCPP shows that so far in Pakistan, the true causative agent (Mccp) of this disease has only been isolated in the Pashin District of Balochistan and that the disease is more frequently confused with other respiratory diseases of goat caused by the Mycoplasma mycoides cluster. The lack of suitable techniques and extensive knowledge in the field is a big limitation for the isolation and characterisation of Mccp from prevailing CCPP-like cases in the goat population of Pakistan.

show abstract

“…General signs, such as weakness, pyrexia, or anorexia, that precede focal localizations often go unnoticed in adults whereas they can rapidly lead to mortality in young animals 48. Arthritis occurs frequently in young animals as a polyarthritis form causing recumbence, especially with Mcc 1,48 and Mmc ,54,55,64,68 but only occasionally in adults, where it causes lameness and swollen joints affecting mainly the tarsus and carpus 6963,69.…”

Section: Clinical Aspectsmentioning

confidence: 99%

“…Arthritis occurs frequently in young animals as a polyarthritis form causing recumbence, especially with Mcc 1,48 and Mmc ,54,55,64,68 but only occasionally in adults, where it causes lameness and swollen joints affecting mainly the tarsus and carpus 6963,69. Conjunctivitis can occur with Ma and less frequently with Mmc and Mcc 1,48 but is not often reported as it does not affect herd performance.…”

Section: Clinical Aspectsmentioning

confidence: 99%

Contagious Agalactia In Sheep And Goats: Current Perspectives

Jaý¹,

Tardy²

2019

VMRR

View full text Add to dashboard Cite

Contagious agalactia (CA) is a disease caused equally by four Mycoplasma species, in single or mixed infections. Clinical signs are multiple, including mastitis, arthritis, keratoconjunctivitis, pneumonia, and septicemia, non-specific, and expressed differently depending whether sheep or goats are affected, on causative mycoplasmas as well as type of husbandry. CA has been reported worldwide and its geographic distribution maps to that of small ruminant breeding areas. However, as current diagnostic tests are expensive and difficult to implement, it is certainly underdiagnosed and prevalence data are only available for a few countries. CA control relies on vaccines, chemotherapy and good herd management practices. It requires long-term commitment but is often unsuccessful, with frequent clinical relapses. The persistence of the etiological agents, despite their overall susceptibility to antimicrobials, comes from their genetic plasticity and capacity to escape the host immune response. The existence of asymptomatic carriers and the numerous sources of infections contribute to rapid spread of the disease and complicate the control and prevention efforts. Here we review all these aspects in order to highlight recent progress made and identify gaps in knowledge or tools needed for better disease management. Discussion also underlines the detrimental effect of contagious agalactia on small ruminant welfare.

show abstract

Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum

Cited by 18 publications

References 16 publications

Contagious caprine pleuropneumonia – a comprehensive review

Contagious caprine pleuropneumonia – a comprehensive review

Contagious caprine pleuropneumonia and its current picture in Pakistan: a review

<p>Contagious Agalactia In Sheep And Goats: Current Perspectives</p>

Contact Info

Product

Resources

About