Mortality in necrotic form of erysipelas

Abstract

Purpose of the study. To find out the mortality rate in patients with necrotic form of erysipelas and the reasons that cause it.
 Materials and metods. 284 case histories of patients who were hospitalized in the center of purulent-septic surgery of KNP «City Hospital
 № 3» in Zaporozhye for the period 2016–2021 were analyzed.
 Results. It is established that in the general population of the disease, 14,1% of patients suffer from the necrotic form of erysipelas. In the complex treatment of patients with surgical forms of erysipelas, the main place belongs to antibiotic therapy (ABT) and early surgical treatment of the area of the pathological process. Determination of procalcitonin in blood serum makes it possible to assess the progression of the inflammatory process and is a sensitive test for the effectiveness of treatment.
 Conclusion. In 72,5% of cases, the disease was aggravated by sepsis with a mortality of 67,5%. The cause of mortality in patients with necrotic erythema is numerous irreversible changes in the internal organs.

Reasons for unsatisfactory results of treatment of destructive forms of erysipelas

“…Все частіше спостерігається зміна клінічної симптоматики та перебігу захворювання з розвитком тяжких ускладнень та сепсису. Летальність серед некротичної форми хвороби коливається в межах від 5,8 до 81% та, як правило, зумовлюється розвитком сепсису [3,4,5,7]. У цьому контексті важливо своєчасно розпізнати розвиток сепсису, оцінити загальний стан хворого та визначити подальшу стратегію лікування.…”

Analysis of Unsatisfactory Consequences of Erysipelas Treatment

“…Changes in clinical symptoms and course of the disease with the development of severe complications and sepsis are increasingly observed. Mortality ranges from 5.8 to 81% for the necrotic form of the disease and is usually caused by sepsis development [3,4,5,7]. From this perspective, it is important to recognize the development of sepsis timely, to assess the patient's general condition and determine further treatment strategy.…”

“…In the structure of the disease, a tendency to an increase in the number of young and middle-aged patients, as well as an increase in complicated forms of erysipelas and its recurrence has been noted [1,2,6].Changes in clinical symptoms and course of the disease with the development of severe complications and sepsis are increasingly observed. Mortality ranges from 5.8 to 81% for the necrotic form of the disease and is usually caused by sepsis development [3,4,5,7]. From this perspective, it is important to recognize the development of sepsis timely, to assess the patient's general condition and determine further treatment strategy.However, unfortunately, a detailed analysis of unsatisfactory results of the treatment of erysipelas complicated forms is absent.The objective of the research was to determine the cause of unsatisfactory treatment results in patients with destructive forms of erysipelas among the overall disease population.…”