Mortality of Elderly Patients After Two-Stage Reimplantation for Total Joint Infection: A Case–Control Study

Webb, Jonathan E.; Schleck, Cathy D.; Larson, Dirk R.; Lewallen, David G.; Trousdale, Robert T.

doi:10.1016/j.arth.2014.04.019

Cited by 21 publications

(18 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As already reported, we found no difference between hip and knee prosthesis but a higher mortality in men compared to women and an increased mortality with age 3,4,7,11-13. Higher mortality due to enterococci has already been hypothesized to be related to the intrinsic antimicrobial resistance to b -lactams which are used as prophylactic antibiotics before revision surgery 7.…”

Section: Discussionsupporting

confidence: 71%

“…(7) Our results are closer to the recent ones by Lum et al (3,9,10) As already reported, we found no difference between hip and knee prosthesis but a higher mortality in men compared to women and an increased mortality with age. (3,4,7,(11)(12)(13) Higher mortality due to enterococci has already been hypothesized to be related to the intrinsic antimicrobial resistance to b-lactams which are used as prophylactic antibiotics before revision surgery. (7) The current study also shows surprisingly, and never described before, that patients treated with a one-stage or two-stage exchange have a lower mortality than the ones treated with debridement and retention.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prosthetic-joint Infections: Mortality Over The Last 10 Years

Fischbacher

Borens

2019

J. Bone Joint Infect.

View full text Add to dashboard Cite

Abstract. Background: There is a constant increase of joint arthroplasties to improve the quality of life of an ever-aging population. Although prosthetic-joint infections are rare, with an incidence of 1-2%, they represent a serious complication in terms of morbidity and mortality. Infection related mortality is known to be approaching 8% at one year. The aim of this retrospective study is to reassess the one and two-year mortality over the last ten years.Methods: Patients treated for prosthetic joint infection at the University Hospital of Lausanne (Switzerland) between 2006 and 2016 were included. The one and two-year cumulative mortality depending on sex, age, type of prosthesis, infecting organism and type of surgical treatment were computed.Results: 363 patients (60% hips, 40% knees) were identified with a median age of 70 years. The one-year cumulative mortality was 5.5% and it was 7.3% after two years. No difference was seen between hip and knee prostheses, but the mortality was higher in men than in women and increased with age. Furthermore, there was a significant difference depending of the germ with enterococci infections associated with a higher risk of death. Finally, patients treated with a one-stage or two-stage exchange had a lower mortality than those treated with debridement and retention.Conclusion: The mortality is still high and differs according to sex, age, infecting organism and type of surgical treatment. There is a need of studies to improve the management of patients at risk of increased mortality.

show abstract

Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 99%

Prosthetic-joint Infections: Mortality Over The Last 10 Years

Fischbacher

Borens

2019

J. Bone Joint Infect.

View full text Add to dashboard Cite

show abstract

“…Patients who undergo revision surgery for PJI have a higher risk of unplanned readmission [19] and longer length of stay [23] compared with patients who undergo revision surgery for other causes, which implies that PJI has a major effect on a patient's health. One study showed that revision for PJI in THAs or TKAs is associated with higher mortality than aseptic revision [27], but not all studies have found this association [4,24]. None of the previous published studies exclusively investigated the associated between revision for early postoperative PJI in primary THA and mortality.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, one study including THA and TKA showed that there is an increased mortality risk within 1 year after revision for PJI [27]. However, not all studies have identified PJI to be associated with a higher mortality risk [4,24], and so far studies of PJI and mortality have been based on a mixture of THA and TKA [24,27], patients from a single institution [4,24,27], and without a maximum defined interval from primary THA surgery to revision for PJI [4,24,27].…”

Section: Introductionmentioning

confidence: 99%

Increased Mortality After Prosthetic Joint Infection in Primary THA

Gundtoft

Pedersen

Varnum

et al. 2017

Clinical Orthopaedics &Amp; Related Research

166

View full text Add to dashboard Cite

show abstract

“…If a busy surgeon treats a few dozen patients a year with PJI of the hip (or even a couple hundred), it would be all-but-impossible for her to discern reliably a doubling or even a tripling of an event that happens to only a few percent of her patients. And even large studies are susceptible to drawing discordant conclusions about rare events [1,3,4], since event-rate estimates in this setting often are beset by wide confidence intervals.…”

mentioning

confidence: 99%

Editor's Spotlight/Take 5: Increased Mortality After Prosthetic Joint Infection in Primary THA

Leopold

2017

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

Mortality of Elderly Patients After Two-Stage Reimplantation for Total Joint Infection: A Case–Control Study

Cited by 21 publications

References 32 publications

Prosthetic-joint Infections: Mortality Over The Last 10 Years

Prosthetic-joint Infections: Mortality Over The Last 10 Years

Increased Mortality After Prosthetic Joint Infection in Primary THA

Editor's Spotlight/Take 5: Increased Mortality After Prosthetic Joint Infection in Primary THA

Contact Info

Product

Resources

About