Mortality patterns among workers exposed to styrene in the reinforced plastic boatbuilding industry: An update

Abstract

We found no excess leukemia or lymphoma mortality. Unanticipated excess urinary tract cancer and respiratory disease mortality, possibly associated with styrene exposure, are difficult to interpret and could be chance findings.

An ecological study of the association of environmental chemicals on breast cancer incidence in Texas

“…Most of these studies, in which women were not included or under-represented, found the relationship between styrene exposure and breast cancer to be null or did not indicate whether this relationship was examined [56][57][58][59][60][61]. In addition, all of these studies focused on styrene exposure rather than the carcinogen, styrene-7,8-oxide, traces of which are generated during the manufacturing of styrene.…”

Occupational exposures to asbestos, polycyclic aromatic hydrocarbons and solvents, and cancers of the oral cavity and pharynx: a quantitative literature review

“…Ruder et al (2004) considered mortality among workers exposed to styrene in the boatbuilding industry, but results were inconclusive because of the small number of observed cases. The study by Lehman and Hein (2006) considered exposure to toluene in a cohort of shoe manufacturing workers, and the results showed slightly increased mortality among men.…”

Occupational Exposures and Haematological Malignancies: Overview on Human Recent Data

“…Styrene, also used in the plastic industry, is considered a possible carcinogenic agent by IARC (group 2B), and its metabolite styrene oxide a probable carcinogen (group 2A). A historical cohort study left open a possible excess risk of leukaemia in styrene-exposed workers [113], but no excess risk of mortality from leukaemia was observed in a cohort study of 5204 such workers [114].…”