Mortality Rate of Acute Stroke in Iran: A Systematic Review and Meta-Analysis

Abstract

Background: There is limited data about the short-term stroke mortality rates for patients in treatment settings. Objectives: This study aimed to estimate the short-term stroke (in hospital, one month, one year) mortality rates in Iran through a systematic review and meta-analysis. Materials & Methods: We searched electronic databases, including three national (IranDoc, Megiran, SID) and four international (Scopus, PubMed, Web of Science, Google Scholar), from January 1990 to March 2020. We considered all observational studies on stroke mortality, such as cohort and crosssectional studies. Furthermore, the sub-group analyses were performed based on each province and metaregression analysis based on the study’s year and patients’ mean age. Results: Among 143 studies, 28 were eligible (11 cohort and 17 cross-sectional studies). Based on the random model, the mortality rates for in-hospital, 1-month, and 1-year mortality were reported as 18.71% (95% CI: 15.09%-22.34%), 23.43% (95% CI: 20.08%-26.78%), and 34.44% (95% CI: 32.02%- 36.85%), respectively. The results also revealed that mortality rates were neither related to the year studies conducted nor to the patient’s age. Conclusion: Approximately one-fifth of stroke patients in Iran die in the hospital after admission. The mortality rate increased in the one-month and one-year period, and about one-third of the patients died in the first year. Therefore, it is cardinal to focus on programs and solutions in which we can ameliorate mortality in the short-term period after stroke by performing primary specific treatments on patients.

Perceived social support, self-management, perceived stress, and post-traumatic growth in older patients following stroke: Chain mediation analysis

“…Increasing evidence has elucidated that increasing age is a crucial risk factor for stroke mortality, especially for the older population, who are more susceptible to physical and emotional challenges. [37] These challenges can trigger heightened perceived stress levels, exacerbating their coping mechanisms following the stroke. [11] In the current study, older poststroke survivors experiencing high levels of perceived stress tended to confront the stroke in a maladaptive manner, showing resistance to accepting their altered reality and exhibiting negative emotional responses like anxiety, fear, and depression.…”

Relationship Between Pain and Disability Among Stroke Patients

“…In Nikbakht et al's meta-analysis study of 17 articles, the hospital mortality rate was 18.71%, and the one-month mortality rate was 23.43% (12). Also, in the study of Krishnamurthi et al, the global prevalence of hemorrhagic stroke was reported as 3,725,085, and the prevalence of ischemic stroke was 7,258,216 (13).…”

Bilirubin: From a Disease Predictor to a Potential Therapeutic in Stroke

“…The most common type of stroke is ischemic stroke, which arises after embolism, thrombolysis, or cryptogenic mechanisms in which blood flow to the brain is damaged. 1 Early prediction of the outcome in patients with ischemic stroke is significant. Reliable prognostic markers existing during the initial phase after acute stroke could help clinical decisionmaking.…”