Mortality rates for extremely low‐birthweight infants: A regional, population‐based study in Japan during 2005–2009

Abstract

Survival of infants (<1000 g) depends on gestational age, centralization and multiple births.

Perinatal morbidity and mortality for extremely low‐birthweight infants: A population‐based study of regionalized maternal and neonatal transport

“…The study subjects consisted of the following patients: maternal transport (primary to secondary center), n = 30; born at a secondary center, n = 48; maternal transport (primary to a tertiary center), n = 34; maternal transport (secondary to tertiary center), n = 68; born at a tertiary center, n = 13; and born at a primary center or at home, n = 2. The detailed characteristics of the mothers and infants have been described previously …”

“…The protocols for obstetric and neonatal management are basically the same at all perinatal centers in Miyazaki. The management methods are described in our previous paper …”

“…When the medical needs of the mother and/or fetus are beyond the scope of the current facility, antepartum maternal referral to a tertiary care center is necessary. In addition, we demonstrated in our previous report that the survival of ELBW infants depends on centralization . However, although tertiary centers may provide the best clinical management for mothers and/or neonates, the number of beds available for mothers and neonates in such centers is limited.…”

Impact of Skin Lesions on Morbidity and Mortality in Extremely Premature Infants in One Tertiary Center in Southern Japan

“…In a previous population-based study on extremely low-birth weight infants, we reported that the perinatal mortality depends on gestational age and centralization, in which the mortality rate was 29% at 22 weeks of gestation, 22% at 23 weeks, 34% at 24 weeks, 7% at 25 weeks, and 6% at 26 weeks [2]. Under these circumstances of perinatal care, we investigated whether the presence or absence of skin lesions may affect neonatal mortality and morbidity in extremely premature infants.…”

“…These outcomes are influenced by many perinatal factors. For example, antenatal factors include obstetrician's attitude [1], gestational age [2], sex [3], antenatal corticosteroid therapy [3], multi fetal pregnancy [4], growth restriction and so on [5,6], and neonatal factors include circulatory and respiratory instability [7], intracranial hemorrhage, Periventricular leukomalacia [8], intestinal perforation [9], and so on.…”