MoS2 nanosheets supported on anodic aluminum oxide membrane: An effective interface for label-free electrochemical detection of microRNA

Yuan, Shuai; Jiang, Zilian; Wang, Yahui; Zhang, Hongfang

doi:10.1016/j.aca.2023.341522

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Advantages and Disadvantages Of Biosensors Based On Nanomate...1

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2024

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Cited by 4 publications

(1 citation statement)

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“…MoS 2 nanowires can not only quench fluorescence but also have a high specific surface area, which has broad prospects in the electrochemical detection of miRNA. Su et al developed another novel electrochemical bioassay platform for MoS 2 nanowires supported by anodic aluminum oxide film 98 ( Fig. 7C ).…”

Section: Advantages and Disadvantages Of Biosensors Based On Nanomate...mentioning

confidence: 99%

Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Ouyang,

Huang,

et al. 2024

RSC Adv.

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Section: Advantages and Disadvantages Of Biosensors Based On Nanomate...mentioning

confidence: 99%

Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Ouyang,

Huang,

et al. 2024

RSC Adv.

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Multi-dimensional engineering of transition metal dichalcogenides for enhanced performance in fuel cell technologies

Dong,

Ma,

Lopez

et al. 2024

Materials Today Energy

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MicroRNA Triggered Dimerization of DNA Tetrahedron for Enhanced Biosensing Performance of Solid-State Nanochannels Functionalized with MoS₂ Nanosheets

Su,

Zhang,

Zhang

2024

ACS Appl. Mater. Interfaces

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Solid-state nanochannels (SSN) have great development potential as a biosensing interface. The integration of two-dimensional nanomaterials with nanochannels endows SSN with diverse properties, including distinguishing DNA nanostructures. In this study, by modifying MoS 2 nanosheets, the outer surface of SSN could be endowed with robust adsorption properties for single-stranded DNA. Therefore, DNA tetrahedrons connected with single-stranded DNA could remain on the SSN surface, whereas DNA tetrahedron dimers with full double-stranded structures formed by the presence of target microRNA cannot be retained on the surface of nanochannels. The change in the DNA nanostructure generated by the target recognition process could cause variations of steric hindrance and electrostatic repulsion on the surface of the SSN. The variations were reflected by the free diffusion flux of [Fe(CN) 6 ] 3− . Then, the sensitive electrochemical detection method for microRNA was established, and the detection limit of the method for microRNA-31 was as low as 0.5 fM. The study provided a promising approach for the ultrasensitive detection of biomarkers, thereby offering potential means for early diagnosis of the related diseases.

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MoS2 nanosheets supported on anodic aluminum oxide membrane: An effective interface for label-free electrochemical detection of microRNA

Cited by 4 publications

References 34 publications

Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Multi-dimensional engineering of transition metal dichalcogenides for enhanced performance in fuel cell technologies

MicroRNA Triggered Dimerization of DNA Tetrahedron for Enhanced Biosensing Performance of Solid-State Nanochannels Functionalized with MoS₂ Nanosheets

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MoS2 nanosheets supported on anodic aluminum oxide membrane: An effective interface for label-free electrochemical detection of microRNA

Cited by 4 publications

References 34 publications

Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Nanomaterials promote the fast development of electrochemical MiRNA biosensors

Multi-dimensional engineering of transition metal dichalcogenides for enhanced performance in fuel cell technologies

MicroRNA Triggered Dimerization of DNA Tetrahedron for Enhanced Biosensing Performance of Solid-State Nanochannels Functionalized with MoS2 Nanosheets

Contact Info

Product

Resources

About

MicroRNA Triggered Dimerization of DNA Tetrahedron for Enhanced Biosensing Performance of Solid-State Nanochannels Functionalized with MoS₂ Nanosheets