Mosquito larvicidal activity of citrus limonoids against Aedes albopictus

Hafeez, Faisal; Akram, Waseem; Shaalan, Essam Abdel-Salam

doi:10.1007/s00436-010-2228-9

Cited by 46 publications

(23 citation statements)

References 26 publications

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“…Our results are in agreement with those reported by Chaithong et al (2006) and Islam et al (2003) against C. quinquefasciatus. Hafeez et al (2011) reported that the liminoids from citrus showed the highest larvicidal activity against A. albopictus.…”

Section: Discussionmentioning

confidence: 98%

A novel herbal formulation against dengue vector mosquitoes Aedes aegypti and Aedes albopictus

Maheswaran¹,

Ignacimuthu²

2011

Parasitol Res

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The objective of this study was to develop a herbal formulation to control dengue vector mosquitoes. PONNEEM, a novel herbal formulation prepared using the oils of neem (Azadirachta indica), karanj (Pongamia glabra) and their extracts, was tested for larvicidal, ovicidal and oviposition deterrent activities against Aedes aegypti and Aedes albopictus at 1, 0.5, 0.3 and 0.1 ppm concentrations. Cent percent larvicidal and ovicidal activities were observed at 0.1 ppm in the two mosquito species under laboratory and sunlight-exposed conditions up to 12 months from the date of manufacture. Oviposition deterrent activity of 69.97% and 71.05% was observed at 1 ppm concentration of PONNEEM against A. aegypti and A. albopictus, respectively. Reduction in enzyme levels for α-esterase was 0.089 ± 0.008 and 0.099 ± 0.140 μg napthol produced/min/mg larval protein; for β-esterase, it was 0.004 ± 0.009 and 0.001 ± 0.028 μg napthol produced/min/mg larval protein; for glutathione S-transferase, it was 10.4814 ± 0.23 and 11.4811 ± 0.21 μmol/min/mg larval protein and for total protein, it was 0.177 ± 0.010 and 0.008 ± 0.005 mg/individual larva in treated groups of A. aegypti and A. albopictus, respectively. The nontarget organisms such as Gambusia affinis and Diplonychus indicus were not affected. No mortality was observed in control. PONNEEM can be used effectively for the management of human vector mosquitoes.

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Section: Discussionmentioning

confidence: 98%

A novel herbal formulation against dengue vector mosquitoes Aedes aegypti and Aedes albopictus

Maheswaran¹,

Ignacimuthu²

2011

Parasitol Res

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“…The unbalanced solubility profile of the latter may explain the relatively low number of studies on their respective biological activities which are hampered by difficult isolation from natural sources and poor pharmacokinetics. Analgesic [45], anticancer [46][47][48][49][50][51][52][53][54][55][56][57][58][59], anti-inflammatory [45,[60][61][62], antibacterial [63,64], antioxidant [4,65,66], antiviral [67], larvicidal [68,69] Anticancer [46,47,58,59,70], anti-hyperglycemic [71], anti-inflammatory [25,62], antioxidant [4,65,66], antiviral [67], larvicidal [68,69] …”

Section: Chemistry and Classificationsmentioning

confidence: 99%

The Chemistry and Pharmacology of Citrus Limonoids

et al. 2016

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Citrus limonoids (CLs) are a group of highly oxygenated terpenoid secondary metabolites found mostly in the seeds, fruits and peel tissues of citrus fruits such as lemons, limes, oranges, pumellos, grapefruits, bergamots, and mandarins. Represented by limonin, the aglycones and glycosides of CLs have shown to display numerous pharmacological activities including anticancer, antimicrobial, antioxidant, antidiabetic and insecticidal among others. In this review, the chemistry and pharmacology of CLs are systematically scrutinised through the use of medicinal chemistry tools and structure-activity relationship approach. Synthetic derivatives and other structurally-related limonoids from other sources are include in the analysis. With the focus on literature in the past decade, the chemical classification of CLs, their physico-chemical properties as drugs, their biosynthesis and enzymatic modifications, possible ways of enhancing their biological activities through structural modifications, their ligand efficiency metrics and systematic graphical radar plot analysis to assess their developability as drugs are among those discussed in detail.

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“…The larval population was reared on TetraMin Tropical (Tetra TM). Adults were reared in steel cages and males were provided with 10% sucrose solution, while females were fed on blood of white rats (albino) [12] . Eggs were laid in plastic cups lined with filter paper then they were separated and shifted to rearing trays.…”

Section: Entomopathogenic Fungusmentioning

confidence: 99%