Background
There is an increasing number of human immunodeficiency virus (HIV) reported cases among students in Southwest China. However, the data on HIV/sex-related knowledge, attitude toward sex, sexual behaviors, and correlates of pre-exposure prophylaxis (PrEP)-eligible behaviors among college students in this area is still limited. This study aimed to assess the prevalence of HIV/sex-related knowledge, sexual attitudes, sexual behaviors, and factors associated with PrEP-eligible behaviors among college students.
Method
An online survey from 2020 to 2021 based on a multistage stratified and cluster sampling method was conducted among college students in Southwest China, and a well-designed questionnaire collected data. Propensity score matching (PSM), logistic, and log-binomial regression were used to identify the determinants of PrEP-eligible behaviors.
Result
A total of 108,987 students participated in the survey, and 92,946 provided valid responses. 91.6% (85,145/92,946) had good HIV-related knowledge, while only 26.0% (24,137/92,946) reported awareness of sex-related knowledge. Furthermore, more than half of the participants (64.5%) held negative stances towards engaging in “one-night stand”, and 58.9% (617/1,047) reported PrEP-eligible behaviors. Log-binomial regression analysis indicated that unaware of HIV-related knowledge (
aPR
= 1.66, 95%
CI
:1.22–2.26,
P
= 0.001), not discussing about sex with their parent(s) (
aPR
= 1.16, 95%
CI
:1.01–1.33,
P
= 0.021), not receiving sex-related education in school(
aPR
= 1.24, 95%
CI
: 1.07–1.45,
P
= 0.005), not participating in HIV/AIDS prevention activities in the past year (
aPR
= 1.32, 95%
C
I:1.09–1.60,
P
= 0.004), experiencing forced sex (
aPR
= 2.08, 95%
CI
: 1.19–3.63,
P
= 0.010), and having the drug abuse (
aPR
= 22.21, 95%
CI
:5.59–88.31,
P
< 0.001) were significantly associated with increased odds of PrEP-eligible behaviors.
Conclusion
College students in Southwest China exhibited suboptimal HIV/sex-related knowledge, received limited sex education, reported conservative attitudes towards casual sex, and significant PrEP-eligible behaviors. These findings suggest that sexually experienced college students who were unaware of HIV-related knowledge, lacked sex education, experienced forced sex, and reported drug abuse were the key individuals for evaluating eligibility for PrEP initiation, and interventions aimed at increasing awareness of HIV/sex-related knowledge, promoting...