Motility Abnormalities in Esophageal Body in GERD

Abstract

Esophageal manometric abnormalities should be considered cautiously before considering a motor disorder as a consequence of abnormal reflux.

Ineffective esophageal motility and gastroesophageal reflux disease: A close relationship?

“…This finding was compatible with the other studies, one of which was performed by Rios et al (22) and demonstrated that hypotensive LES with or without esophageal motor abnormalities was found in more than one-third of GERD patients. They also comment that IEM was the disorder most strongly related to reflux.…”

Esophageal motor disorders are frequent during pre and post lung transplantation. Can they influence lung rejection?

“…Therefore, pH, bile acid and trypsin levels in GERD have been studied as biomarkers for chronic allograft dysfunction (3). GERD is also associated with esophageal motor disorders (EMD), although it is not clear if GERD is the cause or the consequence of the esophageal motility impairment (4). Although GERD has been extensively studied as a factor associated with LTx rejection, there are some gaps with regard to the potential contribution to the abnormal motility of the esophagus.…”