Motion detection and amelioration in a dedicated cardiac solid-state CZT SPECT device

Abstract

A solid-state cadmium zinc tellurium (CZT) dedicated multipinhole cardiac camera which acquires all views simultaneously has been introduced for myocardial SPECT acquisition. We report a method to detect and ameliorate patient motion artifacts in myocardial perfusion imaging (MPI) studies recorded with this device. To detect motion, a myocardial phantom study was recorded, and at mid-scan, the phantom was moved stepwise along each of 6 orthogonal directions, causing MPI artifacts. Using QPS software (Cedars-Sinai) and an in-house normal database, displacements giving artifactual perfusion defects (total perfusion deficit score, TPD, >5 %) were all 1.5 cm or greater (11.2 ± 1.3 % for 1.5 cm). List mode data were reframed into 10-s steps, and the norm of the changes in center of mass among the 19 projections (32 × 32 matrix, pixel size 2.46 mm) was used as a motion index. Rejection of misregistered data gave artifact-free reconstructions (TPD = 1.0 ± 0.8 %) in phantom scans and reduced blur in a rest/stress clinical study. Blur on the patient's stress scan was consistent with increased motion compared to rest (motion index of 4.4 vs. 3.0 pixels, respectively). For CZT cameras that acquire data from multiple views simultaneously, motion during MPI can cause clinically significant artifacts. Reframing acquisitions into discrete time intervals enables the detection of motion and its amelioration, improving diagnostic accuracy.

DuDoCFNet: Dual-Domain Coarse-to-Fine Progressive Network for Simultaneous Denoising, Limited-View Reconstruction, and Attenuation Correction of Cardiac SPECT

“…There are some factors worth attention in cardiac SPECT including motion correction and scatter correction. Motion correction methods for this GE 530c/570c dedicated scanner were investigated by several studies [67]- [70]. The postreconstruction method can also be employed for reducing the respiratory and cardiac motions [71].…”

Highlights lecture EANM 2014: “Gimme gimme gimme those nuclear Super Troupers”

“…In order to realize the ultimate goal of quantitative cardiac SPECT, one important aspect is motion correction, for which solid-state CZT (cadmium zinc telluride) cameras can be sensitive, due to simultaneous multiangle acquisition. Kennedy and Strauss [ 5 ] showed that total perfusion defects can be erroneously large with movements that surpass 10 mm. In such cases, selective rejection of projection data where greatest motion induced blur, results in better image contrast and improved perfusion defect quantification.…”

Solid-State Detector SPECT Myocardial Perfusion Imaging

“…Respiratoryphase-matched CT attenuation maps may further improve image quality and have been shown to significantly improve interobserver agreement compared with uncorrected images (49). Patient motion can also be corrected using a similar approach to reduce the rate of false-positive perfusion defects (50). Dual respiratory/cardiac gated MPI has been demonstrated in phantoms and patients, showing progressive improvement of the myocardium-to-blood-pool contrast with the application of respiratory and then dual gating (48).…”