Motion processing after sight restoration: No competition between visual recovery and auditory compensation

Bottari, Davide; Kekunnaya, Ramesh; Hense, Marlene; Troje, Nikolaus F.; Sourav, Suddha; Röder, Brigitte

doi:10.1016/j.neuroimage.2017.11.050

Cited by 36 publications

(35 citation statements)

References 59 publications

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“…The P1 wave has been hypothesized to be functionally closely related to alpha oscillations by Freunberger et al (2008), who suggested that both alpha activity and the P1 wave might reflect activity connected to the inhibition of neural systems related to ''task-irrelevant brain areas or task-irrelevant stimulus categories'' (p. 2339). As discussed above, Bottari et al (2016Bottari et al ( , 2018 found evidence that alpha oscillatory activity is compromised in CC individuals, suggesting that the neural mechanisms regulating the excitatory-inhibitory balance might be compromised as a result of congenital visual deprivation. Such an imbalance might manifest itself not only as alpha oscillatory deficits, but additionally might underlie the generally reduced P1 amplitude.…”

Section: Discussionmentioning

confidence: 88%

“…Visual deprivation in sensitive phases can permanently alter the ability of the brain to acquire visual functions, and induces far-reaching changes going beyond the visual system even if the absence of vision is only temporary (Lee & Whitt, 2015). Transient, bilateral visual deprivation after birth has been shown to cause wide-ranging impairments in visual acuity (Ellemberg, Lewis, Maurer, Lui, & Brent, 1999), stereopsis (Tytla, Lewis, Maurer, & Brent, 1993), face and object processing (Le Grand, Mondloch, Maurer, & Brent, 2001;Putzar, Hötting, & Röder, 2010;Röder, Ley, Shenoy, Kekunnaya, & Bottari, 2013;Sinha & Held, 2012), and global motion perception (Bottari et al, 2018;Hadad, Maurer, & Lewis, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…However, not all visual functions seem to depend on visual input after birth to the same degree. For example, color perception has been reported to develop normally without developmental experience of color (Brenner, Cornelissen, & Nuboer, 1990;McKyton, Citation: Sourav, S., Bottari, D., Kekunnaya, R., & Röder, B. (2018).…”

Section: Introductionmentioning

confidence: 99%

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Evidence of a retinotopic organization of early visual cortex but impaired extrastriate processing in sight recovery individuals

et al. 2018

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Numerous studies in visually deprived nonhuman animals have demonstrated sensitive periods for the functional development of the early visual cortex. However, in humans it is yet unknown which visual areas are shaped to which degree based on visual experience. The present study investigated the functional organization and processing capacities of early visual cortex in sight recovery individuals with either a history of congenital cataracts (CC) or late onset cataracts (developmental cataracts, DC). Visual event-related potentials (VERPs) were recorded to grating stimuli which were flashed in one of the four quadrants of the visual field. Participants had to detect rarely occurring grating orientations. The CC individuals showed the expected polarity reversal of the C1 wave between upper and lower visual field stimuli at the typical latency range. Since the C1 has been proposed to originate in the early retinotopic visual cortex, we concluded that one basic feature of the retinotopic organization, upper versus lower visual field organization, is spared in CC individuals. Group differences in the size and topography of the C1 effect, however, suggested a less precise functional tuning. The P1 wave, which has been associated with extrastriate visual cortex processing, was significantly attenuated in CC but not in DC individuals compared to typically sighted controls. The present study thus provides evidence for fundamental aspects of retinotopic processing in humans being independent of developmental vision. We suggest that visual impairments in sight recovery individuals may predominantly arise at higher cortical processing stages.

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Section: Discussionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

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Evidence of a retinotopic organization of early visual cortex but impaired extrastriate processing in sight recovery individuals

et al. 2018

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“…This allowed us to investigate how the brain supports unconstrained face-to-face interaction, building on laboratory verbal communication studies that have used either more constrained tasks or lack direct face-to-face interaction (Stephens et al, 2010;Dikker et al, 2014;Cohen et al, 2017;Dumas et al, 2010;Sänger, PM: To paraphrase the provocative title of Asif Ghazanfar and Charles Schroeder"s (2006) paper, large swaths of the neocortex (and subcortex) have the ability to integrate information stimulating multiple senses. Crossmodal convergence as well as, increasingly, multisensory processes are assessed in terms of their utility in the clinics for improving sensory and cognitive deficits (e.g., Amedi et al 2007;Striem-Amit et al 2012;Murray et al 2015;Tinga et al 2016;Vercillo et al 2017;Bottari et al 2018). I believe that the real potential lies here in scrutinizing the interplay between top-down attentional control, object processes, and brain development/plasticity, as it has been done in the purely visual domain (e.g., Astle First, integrative processes can occur at "feedforward" (<100ms post-onset) stages of brain processing, within "sensory specific" cortices, such as V1 (reviewed in e.g.…”

Section: Cpmentioning

confidence: 99%

Are We Ready for Real-world Neuroscience?

Matusz

Dikker

Huth

et al. 2019

Journal of Cognitive Neuroscience

202

176

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Real-world environments are typically dynamic, complex, and multisensory in nature and require the support of top-down attention and memory mechanisms for us to be able to drive a car, make a shopping list, or pour a cup of coffee. Fundamental principles of perception and functional brain organization have been established by research utilizing well-controlled but simplified paradigms with basic stimuli. The last 30 years ushered a revolution in computational power, brain mapping, and signal processing techniques. Drawing on those theoretical and methodological advances, over the years, research has departed more and more from traditional, rigorous, and well-understood paradigms to directly investigate cognitive functions and their underlying brain mechanisms in real-world environments. These investigations typically address the role of one or, more recently, multiple attributes of real-world environments. Fundamental assumptions about perception, attention, or brain functional organization have been challenged-by studies adapting the traditional paradigms to emulate, for example, the multisensory nature or varying relevance of stimulation or dynamically changing task demands. Here, we present the state of the field within the emerging heterogeneous domain of real-world neuroscience. To be precise, the aim of this Special Focus is to bring together a variety of the emerging "real-world neuroscientific" approaches. These approaches differ in their principal aims, assumptions, or even definitions of "real-world neuroscience" research. Here, we showcase the commonalities and distinctive features of the different "real-world neuroscience" approaches. To do so, four early-career researchers and the speakers of the Cognitive Neuroscience Society 2017 Meeting symposium under the same title answer questions pertaining to the added value of such approaches in bringing us closer to accurate models of functional brain organization and cognitive functions.

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“…Sensory input during early years of life is essential for normal development of sensory systems ( Wiesel and Hubel, 1965 ). In humans, studies in individuals treated for congenital cataracts (CC) have revealed incomplete recovery in many visual functions, including visual acuity (VA; Ellemberg et al, 1999 ), stereovision ( Tytla et al, 1993 ), visual feature binding ( Putzar et al, 2007 ; McKyton et al, 2015 ), global motion processing ( Ellemberg et al, 2002 ; Bottari et al, 2018 ), and face processing ( Le Grand et al, 2001 ; Röder et al, 2013 ), while functions such as color discrimination ( Brenner et al, 1990 ; Pitchaimuthu et al, 2019 ) seemed to emerge independently of early visual experience. Biological motion (BM) processing, e.g., the ability to detect the movement of biological figures with sparse information ( Johansson, 1973 ), has been shown to recover well following early visual deprivation ( Hadad et al, 2012 ), that is, both detection thresholds as well as neural signatures have been observed to be indistinguishable between a CC group and normally sighted controls (SC group; Bottari et al, 2015 , 2016 ).…”

Section: Introductionmentioning

confidence: 99%

Biological Action Identification Does Not Require Early Visual Input for Development

Rajendran

Bottari

Shareef

et al. 2020

eNeuro

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Visual input during the first years of life is vital for the development of numerous visual functions. While normal development of global motion perception seems to require visual input during an early sensitive period, the detection of biological motion (BM) does not seem to do so. A more complex form of BM processing is the identification of human actions. Here, we tested whether identification rather than detection of BM is experience dependent. A group of human participants who had been treated for congenital cataracts (CC; of up to 18 years in duration, CC group) had to identify ten actions performed by human line figures. In addition, they performed a coherent motion (CM) detection task, which required identifying the direction of CM amid the movement of random dots. As controls, developmental cataract (DC) reversal individuals (DC group) who had undergone the same surgical treatment as CC group were included. Moreover, normally sighted controls were tested both with vision blurred to match the visual acuity (VA) of CC individuals [vision matched (VM) group] and with full sight [sighted control (SC) group]. The CC group identified biological actions with an extraordinary high accuracy (on average ∼85% correct) and was indistinguishable from the VM control group. By contrast, CM processing impairments of the CC group persisted even after controlling for VA. These results in the same individuals demonstrate an impressive resilience of BM processing to aberrant early visual experience and at the same time a sensitive period for the development of CM processing.

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Motion processing after sight restoration: No competition between visual recovery and auditory compensation

Cited by 36 publications

References 59 publications

Evidence of a retinotopic organization of early visual cortex but impaired extrastriate processing in sight recovery individuals

Evidence of a retinotopic organization of early visual cortex but impaired extrastriate processing in sight recovery individuals

Are We Ready for Real-world Neuroscience?

Biological Action Identification Does Not Require Early Visual Input for Development

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