Background: Multiple Choice Questions (MCQs) are well known and widely used assessment tool. They can be used to measure the different levels of educational outcomes: knowledge, understanding, judgment and problem solving. Traditional MCQs (stand-alone MCQs) often are used as a tool for facts recall. Advantages of using Scenario-based questions (SBQs) include more focus on learning objectives and ability to assess higher levels of learning. Shifting to scenario-based questions can increase the level of difficulty and measure higher levels of cognition. Purpose: This study explores the current knowledge and overall awareness of the undergraduate teaching staff about the use and difficulties of scenario-based single-best answer, multiple-choice questions (SB-SBA-MCQs) in assessments of the basic medical sciences. Method: We used an e-Likert scale questionnaire to explore this issue. The questionnaire covered the current knowledge, experience of staff in writing (SB-SBA-MCQs), courses or postgraduate degrees they attended and difficulties they face or anticipate in writing (SB-SBA-MCQs). Results: The majority (86%) are familiar with courses or workshops related to MCQs writing and assessment in general, a small minority have not attended any. The majority (86%) had some experience in writing MCQs. Only, a small percentage have not tried writing this type of MCQs. Nearly 60% think it takes time to construct, the majority (96%) of those researched are in support of shifting to scenario-based MCQs in basic medical sciences. Conclusion: The study has shown most of the teachers of basic medical sciences are aware of and with good knowledge in (SB-SBA-MCQs). It also highlighted the importance and need for regular training courses and workshops on the same.