The innovation method of college education refers to the development and innovation of college education against the backdrop of current big data (BD), with the goal of having a far-reaching impact on education. The goal of this paper is to investigate and analyze innovative college education methods during the BD and mobile computing eras, in order to find the best solution. This article begins with a general overview of the BD and mobile computing concepts. It then conducted a valid questionnaire survey on the current state of ideological and political courses in two colleges. This paper examines the data and identifies the issues that exist in the ideological and political education in colleges. Finally, it draws the corresponding countermeasures for the innovation mode of college education using BD’s statistical analysis. According to the results of the experiment, 7 percent of college students are more resistant to the ideological and political construction of courses in the current period of BD and mobile computing.