Meta-analysis and structural equation modeling (SEM) are two popular statistical models in the social, behavioral, and management sciences. Meta-analysis summarizes research findings to provide an estimate of the average effect and its heterogeneity. When there is non-trial heterogeneity, moderators such as study characteristics may be used to explain the heterogeneity in the data. On the other hand, SEM includes several special cases, including the general linear model, path model, and confirmatory factor analytic model. SEM allows researchers to test hypothetical models with empirical data. Meta-analytic structural equation modeling (MASEM) is a statistical approach combining the advantages of both meta-analysis and SEM for fitting structural equation models on a pool of correlation matrices. There are usually two stages in the analyses. In the first stage of analysis, a pool of correlation matrices is combined to form an average correlation matrix.In the second stage of analysis, proposed structural equation models are tested against the average correlation matrix. MASEM enables researchers to synthesize researching findings using SEM as the research tool in primary studies. There are several popular approaches to conduct MASEM, including the univariate-r, generalized least squares, two-stage SEM (TSSEM), and one-stage MASEM (OSMASEM). MASEM helps to answer the following key research questions: (1) Are the correlation matrices homogeneous? (2) Do the proposed models fit the data? (3) Are there moderators that can be used to explain the heterogeneity of the correlation matrices? The MASEM framework has also been expanded to analyze large datasets or big data with or without the raw data.