We construct pointed Prym-Brill-Noether varieties parametrizing line bundles assigned to an irreducible étale double covering of a curve with a prescribed minimal vanishing at a fixed point. We realize them as degeneracy loci in type D and deduce their classes in case of expected dimension. Thus, we determine a pointed Prym-Petri map and prove a pointed version of the Prym-Petri theorem implying that the expected dimension holds in the general case. These results build on work of Welters and De Concini-Pragacz on the unpointed case. Finally, we show that Prym varieties are Prym-Tyurin varieties for Prym-Brill-Noether curves of exponent enumerating standard shifted tableaux, extending to the Prym setting work of Ortega.