Motor adjustments during time-constrained sit-to-walk in people with Parkinson's disease

Pelicioni, Paulo Henrique Silva; Pereira, Marcelo Pinto; Lahr, J.; Rodrigues, Mariana M.L.; Morais, Luana Carolina de; Moraes, Renato; Gobbi, Lilian Teresa Bucken

doi:10.1016/j.exger.2019.110654

Cited by 7 publications

(5 citation statements)

References 28 publications

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“…In our assessment of older adults with PD using the MSOA, these participants showed a greater chance (OR 127.6) of presenting general motor aptitude (GMA) impairment than those without PD. These deficits are consistent with characteristic neurological changes resulting from PD that are concentrated on structural damages to the prefrontal cortex, supplementary motor area, sensorimotor cortex, and subcortical regions such as the striatum, basal ganglia, and midbrain, in addition to neurophysiological impairments of the sensorimotor circuit (Pelicioni et al, 2019) and neurochemical and neurotransmitter changes (Goldman & Sieg, 2020).…”

Section: )supporting

confidence: 73%

“…In addition, cognitive deficits, especially executive functions, have been identified among older people with PD (Goldman & Sieg, 2020), mainly related to the loss of dopaminergic neurons in the substantia nigra (Balestrino & Schapira, 2020; Dadar et al, 2020). The association between motor and cognitive impairments negatively influences movement quality in these individuals, largely through problems in planning, programming, and executing motor actions (Kawasaki et al, 2018; Pelicioni et al, 2019). These cognitive-motor processing declines affect the daily lives of individuals with PD and directly affect their motor aptitude (Fernie et al, 2019; Sperens et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

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The Impact of Parkinson’s Disease on General and Specific Motor Aptitudes: A Study of Older Brazilian Adults

et al. 2022

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This study investigated motor aptitude in older adults with and without Parkinson's disease (PD) to further specify known motor-related changes of PD. We divided 671 older adults (23.5% male; Mage = 69.6, SD = 6.6 years) into a Parkinson's Disease Group (PDG) and a non-Parkinson's Disease Group (NPG) and assessed their general motor aptitude (GMA) and their specific motor aptitudes (in Coordinative, Proprioceptive, and Perceptive domains) using the Motor Scale for Older Adults. We used the chi-squared tests and logistic regression to identify and affirm an associations between PD and motor aptitude, we found that most adults without PD showed normal motor aptitude (GMA: 80.7%; Proprioceptive: 82.3%; Perceptive: 81.4%) except for the Coordinative skills, for which 56.4% of these participants had motor impairment. Most partipants with PD showed motor impairments (GMA: 94.7%; Coordinative: 97.4%; Proprioceptive: 97.4%), except in the Perceptive domain, for which 68.4% of participants with PD showed normal aptitude. There were significant associations between PD and GMA (OR = 127.6), Coordinative motor skills (OR = 48.0), and Proprioceptive skills (OR = 204.4), even after the model was adjusted for gender and age. Our use of the Motor Scale for Older Adults in contrasting groups of older Brazilian adults provides further specificity to the motor aptitude characteristics of older adults with PD.

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Section: )supporting

confidence: 73%

Section: Introductionmentioning

confidence: 99%

The Impact of Parkinson’s Disease on General and Specific Motor Aptitudes: A Study of Older Brazilian Adults

et al. 2022

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“…Extrapolating our results to functional tasks, muscle weakness and reduced force development are associated with poor functional performance in the general population [ 38 , 39 , 40 ] and people with PD [ 21 ]. These deficits are more evidenced in people with PD because impairments accompany muscle weakness and deficiencies in the RFD in functionality, impaired muscle strength, and its development, and might, at least, partially explain the evident deficits in the mobility of these individuals, such as on obstacle avoidance and sit-to-walk [ 15 , 16 , 41 ]. These deficits also explain the difficulty in sustaining repetitive muscle contraction as found in previous research [ 42 ], which may increase the risk of falls in people with PD compared to their healthy peers [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Force Production in Parkinson’s Disease Subtypes

Pelicioni

Pereira

Lahr

et al. 2021

IJERPH

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Muscle weakness is a secondary motor symptom of Parkinson’s disease (PD), especially in the subtype characterized by postural instability and gait difficulty (PIGD). Since the PIGD subtype also presents worse bradykinesia, we hypothesized that it also shows a decreased rate of force development, which is linked to an increased risk of falling in PD. Therefore, we investigated the effects of PD and PD subtypes on a force production profile and correlated the force production outcomes with clinical symptoms for each PD subtype. We assessed three groups of participants: 14 healthy older adults (OA), 10 people with PD composing the PIGD group, and 14 people with PD composing the tremor-dominant group. Three knee extension maximum voluntary isometric contractions were performed in a leg extension machine equipped with a load cell to assess the force production. The outcome measures were: peak force and rate of force development (RFD) at 50 ms (RFD50), 100 ms (RFD100), and 200 ms (RFD200). We observed lower peak force, RFD50, RFD100, and RFD200 in people with PD, regardless of subtypes, compared with the OA group (p < 0.05 for all comparisons). Together, our results indicated that PD affects the capacity to produce maximal and rapid force. Therefore, future interventions should consider rehabilitation programs for people with PD based on muscle power and fast-force production, and consequently reduce the likelihood of people with PD falling from balance-related events, such as from an unsuccessful attempt to avoid a tripping hazard or a poor and slower stepping response.

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“…40,41 Such assumptions are supported by data from neurological populations, such as Parkinson's disease and thalamic disease, where these patients show deficits in postural and gait control when these areas are affected. 42,43,44,45 Similarly, neurological COVID-19-related symptoms might also affect motor control. Myalgias may acutely impair the movement execution.…”

Section: Discussionmentioning

confidence: 99%

COVID-19 and its impact on human motor control

Pelicioni¹,

Santos

Tako

et al. 2021

BJMB

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COVID-19 is affecting people differently worldwide with its impact ranging from pneumonia, acute respiratory distress syndrome to death. The direct and indirect effects of COVID-19 on a person’s motor control including on the execution of balance and gait tasks varies. This paper outlines why this may occur and explores neurological complications, mental health, cardiorespiratory complications, hospitalization and reduced physical activity level from COVID-19, and how these issues might affect human motor control. This paper also suggests how these issues may be minimised through strategies such as telehealth and physical exercise programs.

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Motor adjustments during time-constrained sit-to-walk in people with Parkinson's disease

Cited by 7 publications

References 28 publications

The Impact of Parkinson’s Disease on General and Specific Motor Aptitudes: A Study of Older Brazilian Adults

The Impact of Parkinson’s Disease on General and Specific Motor Aptitudes: A Study of Older Brazilian Adults

Assessment of Force Production in Parkinson’s Disease Subtypes

COVID-19 and its impact on human motor control

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