Motor and non-motor correlates of olfactory dysfunction in Parkinson's disease

Berendse, Henk W.; Roos, Dareia S.; Raijmakers, Pieter; Doty, Richard L.

doi:10.1016/j.jns.2011.06.020

Cited by 113 publications

(103 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…By using UPSIT, Berendse and colleagues found that there was a weak but statistically significant negative correlation between UPSIT score and disease duration [25]. In our study, we did not find a similar connection.…”

Section: Itemcontrasting

confidence: 88%

Application of odor identification test in Parkinson's disease in China: A matched case-control study

Chen¹,

Chen²,

Kang³

et al. 2012

Journal of the Neurological Sciences

View full text Add to dashboard Cite

Section: Itemcontrasting

confidence: 88%

Application of odor identification test in Parkinson's disease in China: A matched case-control study

Chen¹,

Chen²,

Kang³

et al. 2012

Journal of the Neurological Sciences

View full text Add to dashboard Cite

“…This study was unique in the use of PET scans to confirm the presence of nigrostriatal nerve terminal losses in all patients, whereas previous studies have only partially used dopamine transporter scans to improve the accuracy of the diagnosis of PD (Haehner et al 2009; Berendse et al 2011). Our findings show a high rate of impaired olfaction, 97.8%, in PD subjects based on age-independent normative cutoff values.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of impaired odor identification in Parkinson disease with imaging evidence of nigrostriatal denervation

et al. 2016

View full text Add to dashboard Cite

There is wide variability in reported prevalence rates of abnormal smell in Parkinson disease (PD). This study assessed the prevalence of abnormal smell, using the University of Pennsylvania Smell Identification Test (UPSIT), in 183 patients with PD with confirmed PET imaging evidence of nigrostriatal denervation. Impaired olfaction in this sample was nearly universal (97.8%). Wide-ranging prior olfactory impairment estimates may reflect not only uncertainty regarding diagnostic classification, but also the use of inaccurate normative data and differences in olfactory tests used.

show abstract

“…--Greater prevalence of fatigue[147,148] (not confirmed in other studies [149-151]), anxiety[152], and impulsive behavior[153], and hyposmia[154]…”

Section: Figmentioning

confidence: 99%

A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015

Chahine

Amara

Videnović

2017

Sleep Medicine Reviews

273

249

View full text Add to dashboard Cite

Sleep disorders are among the most common non-motor manifestations in Parkinson’s disease (PD) and have a significant negative impact on quality of life. While sleep disorders in PD share most characteristics with those that occur in the general population, there are several considerations specific to this patient population regarding diagnosis, management, and implications. The available research on these disorders is expanding rapidly, but many questions remain unanswered. We thus conducted a systematic review of the literature published from 2005-2015 on the following disorders of sleep and wakefulness in PD: REM sleep behavior disorder, insomnia, nocturia, restless legs syndrome and periodic limb movements, sleep disordered breathing, excessive daytime sleepiness, and circadian rhythm disorders. We discuss the epidemiology, etiology, clinical implications, associated features, evaluation measures, and management of these disorders. The influence on sleep of medications used in the treatment of motor and non-motor symptoms of PD is detailed. Additionally, we suggest areas in need of further research.

show abstract

Motor and non-motor correlates of olfactory dysfunction in Parkinson's disease

Cited by 113 publications

References 22 publications

Application of odor identification test in Parkinson's disease in China: A matched case-control study

Application of odor identification test in Parkinson's disease in China: A matched case-control study

Prevalence of impaired odor identification in Parkinson disease with imaging evidence of nigrostriatal denervation

A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015

Contact Info

Product

Resources

About