“…We found that in vitro molecular crowding agents, such as PEG, drove these proteins into spherical droplets that displayed liquid-like properties: they fused with each other over time, wetted the microtubule surface, transferred from one microtubule to another and were transported by Tea2 motor activity towards microtubule plus-ends. This behaviour shows similarity to the previously observed transfer of end-tracking protein clusters from a microtubule end to a solid barrier (Taberner and Dogterom, 2019), and might be relevant in vivo for the cortical deposition of polarity markers that are crucial for the physiology of fission yeast such as Tea1, Tea4, and Tea3 in addition to Mal3, Tea2, and Tip1 (Behrens and Nurse, 2002; Feierbach et al, 2004; Meadows et al, 2018; Snaith et al, 2005; Snaith and Sawin, 2003).…”