1980
DOI: 10.1136/jnnp.43.1.46
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Motor neurone disease and hyperthyroid Graves' disease: a chance association?

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1982
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Cited by 22 publications
(3 citation statements)
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“…However, our ndings indicated no association between GD and T1DM, while AD and GD were protective factors for each other. Besides, the available literature does not provide any large observational studies on asthma and ALS, however, there is evidence of co-occurrence with GD [38,39]. And GWAS identi es shared genetic components between asthma and GD, while the MR results suggested that GD was a protective factor for asthma [40].…”
Section: Discussionmentioning
confidence: 99%
“…However, our ndings indicated no association between GD and T1DM, while AD and GD were protective factors for each other. Besides, the available literature does not provide any large observational studies on asthma and ALS, however, there is evidence of co-occurrence with GD [38,39]. And GWAS identi es shared genetic components between asthma and GD, while the MR results suggested that GD was a protective factor for asthma [40].…”
Section: Discussionmentioning
confidence: 99%
“…There are also rare reports of hyperparathyroidism presenting as a lower motor neuron syndrome, which may be suspected from abnormal calcium or phosphate levels in a routine chemistry panel . It may, therefore, be reasonable to screen for these respective conditions in cases presenting with upper or lower motor neuron dysfunction, but it should be remembered that the presence of these disorders does not rule out the diagnosis of ALS …”
Section: Discussionmentioning
confidence: 99%
“…T RIGGS : In the absence of motor conduction block I shall conclude that this patient had a motor neuron disease, but several clinical syndromes that resemble motor neuron disease and may be associated with various toxic and metabolic perturbations affecting the motor neuron warrant brief consideration. These syndromes include conditions caused by exposure to heavy metals, 8 insulin-secreting tumors, 9 hyperparathyroidism, 10 hyperthyroidism, 11 and infection with the human immunodeficiency virus (HIV). 12 This man, however, had no evidence of either exposure to toxins or endocrine dysfunction; the results of testing for antibodies to HIV are not available, but HIV infection is not a serious consideration in this case.…”
mentioning
confidence: 99%