“…(94, 95) These improvements in intra-limb coordination are accompanied by a significant reduction in patients' variability(94) and improvement in the smoothness(95) of their motor performance. Interestingly, the 3D-kinematic improvements closely follow the clinical time course of impairments such as synergism(94, 96, 97) and are also restricted to the first 3 months post stroke. (98, 99) Interestingly, the present meta-analysis further suggests that the effects of mCIMT on motor function of the arm such as FMA-arm scores is restricted to trials that started within this time window of 3 months post stroke (Table 1 and supplementary web appendix 6 and 7) (References (34, 45, 49, 50, 82)).…”