“…Owing to the novelty of MSE, data on its safety are still relatively scarce [5,6]. To our knowledge, to this date, the safety evidence is based on approximately 1190 patients from 14 studies [1,3,7,8,9,10,11,12,13,14,15,16,17,18]. Large studies like the currently ongoing prospective multicentric "GPS-Registry" under the guidance of Professor Allgaier and Dr. Steinbrück (Freiburg, Germany) will help to further expand data on its performance in the true clinical setting.…”