Moving dynamics of a nanorobot with three DNA legs on nanopore-based tracks

Sun, Li-Zhen; Ying, Yao-Jun

doi:10.1039/d3nr03747a

Nanoscale

2023

DOI: 10.1039/d3nr03747a

|View full text |Cite

Moving dynamics of a nanorobot with three DNA legs on nanopore-based tracks

Li-Zhen Sun,

Yao-Jun Ying

Abstract: DNA nanorobots have garnered increasing attention in recent years due to their unique advantages of modularity and algorithm simplicity. To accomplish specific tasks in complex environments, various walking strategies are...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 107 publications

(138 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Field Driven Polymer Translocation Through a Nanochannel

Bekana,

Asfaw,

Woldemariam

et al. 2024

Journal of Computational and Theoretical Transport

View full text Add to dashboard Cite

Field Driven Polymer Translocation Through a Nanochannel

Bekana,

Asfaw,

Woldemariam

et al. 2024

Journal of Computational and Theoretical Transport

View full text Add to dashboard Cite

Translocation of Gaussian polymers across a nanometric cylindrical channel

Vélez-Pérez,

Olivares-Quiroz

2024

Phys. Scr.

View full text Add to dashboard Cite

We present an analytical model to study translocation of Gaussian polymers across a cylindrical channel of nanometric size with a chemical potential inside the channel.Results show that polymer conformational entropy generates an entropic M-like free energy barrier for translocation.The presence of a small negative chemical potential reduces the entropic free energy barrier rendering the translocation time to follow a power law $\tau = A N^{\nu}$ as function of polymer size $N$.Power law exponents $\nu$ found here in varying the channel radius $R$, run from 1.525 to 1.999 for unforced translocation, and from 1.594 to 2.006 for translocation with small chemical potentials when $R=\SI{1}{\nano\meter}$.Presence of large negative chemical potentials generate a free energy well rendering the translocation time to follow an exponential growth $\tau = A e^{\alpha N}$.We show existence of a negative chemical potential $\mu_c$ that minimizes the translocation time due to an interplay of conformational entropy and channel-polymer interactions.The translocation time as function of channel length $L$ grows exponentially as $\tau = A e^{cL}$, it runs from milliseconds up to decades in the range of lengths found in biological channels.Interestingly, small negative chemical potentials approaching $\mu_c$ overcome the effect of large channel lengths reducing the translocation time below seconds.Translocation speeds $<v(N)>$ show a maximum of micrometers per second then it decays with polymer size and channel length, the characteristic decay $<v(N)>\sim N^{-1}$ has been observed in previous experiments of voltage-driven DNA translocation.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Moving dynamics of a nanorobot with three DNA legs on nanopore-based tracks

Abstract: DNA nanorobots have garnered increasing attention in recent years due to their unique advantages of modularity and algorithm simplicity. To accomplish specific tasks in complex environments, various walking strategies are...

Cited by 2 publications

References 107 publications

Field Driven Polymer Translocation Through a Nanochannel

Field Driven Polymer Translocation Through a Nanochannel

Translocation of Gaussian polymers across a nanometric cylindrical channel

Contact Info

Product

Resources

About