Objectives
Prenatal diagnosis of critical congenital heart disease, that requiring surgical or catheter intervention in the first 30 days of life, allows for delivery at a specialized center which can reduce preoperative morbidity and mortality. We sought to identify risk factors for a missed prenatal diagnosis of critical congenital heart disease.
Methods
Patients presenting to the Children’s Hospital of Wisconsin with critical congenital heart disease from 2007-2013 were included. Those with a prenatal diagnosis were compared to those with a postnatal diagnosis.
Results
The cohort included 535 patients with prenatal diagnosis made in 326 (61%). The prenatal diagnostic rate improved from 44% in 2007 to 69% in 2013. Independent factors associated with a postnatal diagnosis were a lesion that required a view other than a 4 chamber view to make the diagnosis (p<0.0001), absence of another organ system anomaly (p<0.0001), and living in a higher poverty (p=0.02) or lower population density communities (p=0.002).
Conclusions
While the prenatal diagnostic rate for critical congenital heart disease is improving, those living in impoverished or rural communities are at highest risk of not having a diagnosis made prenatally. Interventions to improve prenatal detection of congenital heart disease should target these vulnerable areas.