Moxidectin Efficacy in a Goat Herd with Chronic and Generalized Sarcoptic Mange

Abstract

A case of sarcoptic mange affecting almost all the animals of a dairy goat herd is described. This pruritic skin disease led progressively to high mortality and dramatic drop of milk yield. The lesions of the affected goats were typical of a chronic and generalized-diffuse sarcoptic mange. Diagnosis was confirmed by skin scrapings and histopathology in which many mites were demonstrated. All surviving goats were treated with injectable moxidectin solution 1% (CYDECTIN-Fort Dodge) at the dose of 0.2 mg/kg, applied every 15 days for four times, subcutaneously. Although pruritus had decreased soon after the first treatment, a satisfactory healing of cutaneous lesions was witnessed 6 weeks after the beginning of moxidectin trial. Parasitological cure was achieved in all affected animals by the end of the trial. In the four monthly followups, no evidence of sarcoptic mange could be found.

Effect of Systemic Ivermectin on Epidermal Tunnel Size, Severe Asthetic Appearance of Skin, Haematological and Biochemical Inbalances Caused by Sarcoptes scabie var caprae in West African Dwarf Goats, in Ibadan, Nigeria

“…The pretreatment investigation of this study revealed severe gross and histopathological lesions in the epidermis of the Sarcoptes scabie naturally infested goats, which lead to serious adverse aesthetic and physical effect on the skin quality of the animals as healing of these lesions was by scar formation which was visible on the skin, as this is in agreement with the observation of Gbolagade et al (2009) and Nektarios et al (2011).…”

“…The numerous epidermal tunnels with varying heights and diameter which was observed in the goats prior to commencement of treatment is possibly due to the burrowing ability of these mites into the skin as they feed on tissue fluids and continuously lay eggs in these tunnels which resultantly cause irritation and consequent scratching leading to inflammation and exudation that forms on the skin as this also was observed by Morris et al (1996), Aikten (2007), Nektarios et al (2011) andFalohun et al (2015).…”

Treatment and control of scabies

“…Widely used in veterinary practice, it has recently been proven to be a well tolerated and effective acaricide against mange in goats and sheep [28,29]. Widely used in veterinary practice, it has recently been proven to be a well tolerated and effective acaricide against mange in goats and sheep [28,29].…”

Amelioration of Sarcoptic Mange-Induced Oxidative Stress and Apoptosis in Dogs by UsingCalendula officinalisFlower Extracts

“…Sarcoptic mange is a highly contagious and pruritic acariosis of the skin affecting abroad host range including more than 100 mammalian species belonging to 27 families from 10 orders [1,2] and afflicts 300 million people globally. In many animal species, the prevalence of sarcoptic mange is very high and an untreated animal often succumbs [3,4]. In addition to its potential to cause huge economic loss due to reduced production and increased mortality in animals, [1,5] it is an emerging/reemerging infectious disease that threatens human and animal health globally [6][7][8].…”