Mp64-06 Upper Tract Urothelial Carcinoma Located in the Renal Pelvis Has Worse Clinical Outcomes Compared to the Ureter: A Population-Based Analysis

Abstract

above criteria. The mean tumor size in this age group was 3.5 cm. Overall post-operative complication rate in this group was 28.3%. On univariate analysis, frailty (21.1% vs 5.9%; p ¼ 0.0001), CCI > 5 (32.5% vs 15.8%; p < 0.0001) and EBL (242 cc vs 195 cc, p ¼ 0.026) were found to be statistically associated with a higher rate of major complication. In this cohort, patients 75 years and older were not found to have a higher risk of minor or major complications (table 1). On multivariate analysis, frailty (OR 3.45, p ¼ 0.003, 95% CI 1.52-7.87) was the only variable found to be an independent predictor of major post-operative complication (table 2).CONCLUSIONS: Older patients with renal masses represent a unique population when considering operative management. In our large series of RPN, frailty (based on fall risk due to gait instability or inability to perform activities of daily living) is independently associated with a higher risk of major post-operative complication. This should be considered when counseling these patients on surgery and non-operative alternatives for the management of their renal masses.