MP77-16 PHENOTYPIC VIRULENCE TRAITS, PHYLOGENETIC GROUPING AND PREVALENCE OF PATHOGENICITY ISLAND MARKERS GENES IN
ESCHERICHIA COLI
ISOLATES FROM PATIENTS WITH ORTHOTOPIC ILEAL NEOBLADDER
Abstract:INTRODUCTION AND OBJECTIVE:The malX gene was identified in uropathogenic Escherichia coli (UPEC) strain CFT073 as part of a pathogenicity-associated island about 20 years ago. Homology analysis indicated that it is a component of the phosphotransferase system (PTS) of carbohydrate transport. We compiled the evidence that correlates malX to UTIs. To determine its function, which is unknown, we constructed and characterized mutants lacking malX.METHODS: We compiled all published information about the presence of… Show more
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