MR angiography in carotid stenosis: A comparison of three techniques

Scarabino, Tommaso; Carriero, Alessandro; Magarelli, Nicola; Florio, F; Giannatempo, G.M.; Bonomo, Lorenzo; Salvolini, U.

doi:10.1016/s0720-048x(97)00121-6

Cited by 60 publications

(33 citation statements)

References 22 publications

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“…When compared with digital subtraction angiography for detection of cervical and intracranial stenoses, sensitivity and specificity have ranged from 70% to 100%. 146,147 In the intracranial vasculature, MR angiography is useful in identifying acute proximal large-vessel occlusions but cannot reliably identify distal or branch occlusions.…”

Section: Multimodal Mrimentioning

confidence: 99%

Guidelines for the Early Management of Adults With Ischemic Stroke

Adams¹,

Zoppo²,

Alberts³

et al. 2007

Circulation

1,063

745

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Purpose-Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included. Key Words: AHA Scientific Statements Ⅲ emergency medical services Ⅲ stroke Ⅲ acute cerebral infarction Ⅲ tissue plasminogen activator †Deceased. The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest. Methods-Members

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Section: Multimodal Mrimentioning

confidence: 99%

Guidelines for the Early Management of Adults With Ischemic Stroke

Adams¹,

Zoppo²,

Alberts³

et al. 2007

Circulation

1,063

745

View full text Add to dashboard Cite

show abstract

“…For bright blood angiographic imaging, the 3D approach represents a natural combination with fast gradient-echo sequences. It has been shown that 3D TOF angiography produces superior quality of carotid arteriograms as compared to 2D TOF or phase-contrast sequences (45). Ultrafast 3D gradient-echo sequences with elliptic-centric phase encoding represent the method of choice for acquisition in the first-pass contrast-enhanced MRA (46,47).…”

Section: Imaging Pulse Sequencesmentioning

confidence: 99%

MRI of atherosclerosis in clinical trials

et al. 2006

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Magnetic resonance imaging (MRI) of the arterial wall has emerged as a viable technology for characterizing atherosclerotic lesions in vivo, especially within carotid arteries and other large vessels. This capability has facilitated the use of carotid MRI in clinical trials to evaluate therapeutic effects on atherosclerotic lesions themselves. MRI is specifically able to characterize three important aspects of the lesion: size, composition and biological activity. Lesion size, expressed as a total wall volume, may be more sensitive than maximal vessel narrowing (stenosis) as a measure of therapeutic effects, as it reflects changes along the entire length of the lesion and accounts for vessel remodeling. Lesion composition (e.g. lipid, fibrous and calcified content) may reflect therapeutic effects that do not alter lesion size or stenosis, but cause a transition from a vulnerable plaque composition to a more stable one. Biological activity, most notably inflammation, is an emerging target for imaging that is thought to destabilize plaque and which may be a systemic marker of vulnerability. The ability of MRI to characterize each of these features in carotid atherosclerotic lesions gives it the potential, under certain circumstances, to replace traditional trials involving large numbers of subjects and hard end-points -heart attacks and strokes -with smaller, shorter trials involving imaging end-points. In this review, the state of the art in MRI of atherosclerosis is presented in terms of hardware, image acquisition protocols and post-processing. Also, the results of validation studies for measuring lesion size, composition and inflammation will be summarized. Finally, the status of several clinical trials involving MRI of atherosclerosis will be reviewed.

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“…Second, patients enrolled in our study underwent various ways of angiographic evaluation. Although the accuracy of 1.5 T, 3.0 T MRA and catheter-based DSA was similar (the sensitivity and specificity was 88-100 and 90-100%, respectively, for 1.5 T MRA compared with DSA [26,27,28,29,30,31]. 3.0 T MRA was slightly better than 1.5 T, but without direction comparison with DSA to the best our knowledge [32]) they were anyway not completely consistent.…”

Section: Discussionmentioning

confidence: 99%

Correlation between ABCD, ABCD2 Scores and Craniocervical Artery Stenosis in Patients with Transient Ischemic Attack

Sun

Dai²,

Xiong³

et al. 2013

Eur Neurol

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Background and Purpose: Craniocervical artery stenosis is an important etiology for transient ischemic attack (TIA). We hypothesized ABCD and ABCD2 scores can predict craniocervical artery stenosis in patients with TIA. Methods: ABCD and ABCD2 scores were calculated in a total of 479 consecutive first-ever TIA patients in Nanjing Stroke Registry Program and compared with angiographic imaging derived from MRI or invasive catheter-based angiography. Results: Overall craniocervical artery (O-CA) stenosis was found in 197 (41.1%) patients. Extracranial craniocervical artery (E-CA) and intracranial craniocervical artery (I-CA) stenosis was found in 101 (21.1%) and 110 (23%) cases, respectively. ABCD and ABCD2 scores with similar accuracy for O-CA (AUC_ABCD 0.71, AUC_ABCD2 0.70), E-CA (AUC_ABCD 0.72, AUC_ABCD2 0.72) and I-CA stenosis (AUC_ABCD 0.62, AUC_ABCD2 0.62) were both independent predictors for various categories of artery stenosis after being adjusted for non-ABCD2 parameters. The cut-off points were equally 4 in both predicting rules. For ABCD, sensitivity was 57.4, 65.3 and 52.7% and specificity 77.0, 70.4 and 67.5% for O-CA/E-CA/I-CA, respectively. For ABCD2, sensitivity was 61.9, 69.3 and 58.2% and specificity 72.3, 65.6 and 63.1%. Conclusions: In patients with TIA, despite an association between ABCD and ABCD2 scores and underlying craniocervical artery stenosis, the clinical utility was limited by unsatisfactory sensitivity and specificity.

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MR angiography in carotid stenosis: A comparison of three techniques

Cited by 60 publications

References 22 publications

Guidelines for the Early Management of Adults With Ischemic Stroke

Guidelines for the Early Management of Adults With Ischemic Stroke

MRI of atherosclerosis in clinical trials

Correlation between ABCD, ABCD2 Scores and Craniocervical Artery Stenosis in Patients with Transient Ischemic Attack

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