MR Cholangiopancreatographic Differentiation of Benign and Malignant Intraductal Mucin- Producing Tumors of the Pancreas

Abstract

In patients with intraductal mucin-producing tumors of the pancreas, filling defects are indicative of malignancy. Diffuse main pancreatic duct dilatation greater than 15 mm (main duct type), or any main pancreatic duct dilatation (branch duct type), is strongly associated with malignancy.

Intraductal Papillary Mucinous Neoplasm (IPMN) of the pancreas: a case study and review of literature

“…Understanding of IPMNs has increased substantially since 2000, when Irie et al reported a series of radiological parameters that could indicate degeneration [9]. The study was interesting for two reasons: the first being that the mean age of these patients is rather high, between sixth and seventh decade, with a consequent risk of co-morbidity, while the second was related to the necessity of extensive pancreatic surgery for a neoplasm with a slow evolution.…”

Favorable Response After Gemcitabine-Radiotherapy for Invasive Pancreatic Intraductal Papillary Mucinous Neoplasm: A Case Report

“…It was recently reported that one of the acceptable predictive signs of malignancy for branch duct IPMNs is a size greater than 30 mm plus the presence of mural nodules or protruding lesions in dilated branch ducts, [18][19][20][21] whereas surgical treatment is recommended for main duct variants.…”

Endoscopic Ultrasonography in Management of Cystic Disease of the Pancreas

“…Magnetic Resonance Imaging (MRI) of the pancreas could have better diagnostic performance in differentiating mucinous from non-mucinous cysts in comparison with the CT scan [31]. In addition, MRI enables more characterization of cyst features suggestive of malignancy such as mural nodule, thick septae, solid component or main pancreatic duct dilation [32,33]. However, studies comparing the relative accuracy of MRI and CT scan in differentiating benign from malignant cysts did not show any difference between the two modalities.…”