MR differentiation of low-grade chondrosarcoma from enchondroma

Choi, Bomi; Jee, Won Hee; Sunwoo, Hee Jung; Cho, Jae Hyun; Kim, Jee Young; Chun, Kyung Ah; Hong, Suk Joo; Chung, Hye Won; Sung, Mi Sook; Lee, Yeon Soo; Chung, Yang Guk

doi:10.1016/j.clinimag.2012.08.006

Cited by 64 publications

(50 citation statements)

References 21 publications

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“…Note that the use of scalloping in the diagnosis is limited when examining the metaphyseal region because the cortex is thin, especially in the proximal fibula [29]. In a recent study the predominantly intermediate signal on T1-weighted images [72% (13/18) in low-grade chondrosarcoma vs. 25% (4/16) in enchondroma], multilocular appearance on contrast-enhanced T1-weighted images [83% (15/18) vs. 44% (7/16)] was also discussed for differentiating low-grade chondrosarcoma from enchondroma [50].…”

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confidence: 99%

Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up

Herget¹,

Strohm²,

Rottenburger³

et al. 2014

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confidence: 99%

Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up

Herget¹,

Strohm²,

Rottenburger³

et al. 2014

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“…The presence of bone tissue within the histopathologically identified lesion is potentially useful to differentiate enchondromas from low-grade intramedullary chondrosarcomas (15,16,23) , but the applicability of such a concept in cases of MRI is still to be determined. In fact, the presence of foci of high signal intensity on MRI T1-weighted sequences, suggesting the presence of bone marrow within cartilaginous lesions, has not shown to be useful to differentiate such histological lesion types in at least two previous studies (17,24) . The coexistence of both histological types in a single lesion could explain the identification of foci of bone marrow signal also in chondrosarcomas.…”

Section: Discussionmentioning

confidence: 99%

Incidental enchondromas at knee magnetic resonance imaging: intraobserver and interobserver agreement and prevalence of imaging findings

et al. 2013

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Objective: To evaluate intra-and interobserver agreement in the identification of incidental enchondromas at knee magnetic resonance imaging, and to assess the prevalence of imaging findings. Materials and Methods: Retrospective study reviewing 326 knee magnetic resonance images acquired in the period between November 2009 and September 2010. The images were independently and blindly analyzed by two specialists in musculoskeletal radiology, with the objective of identifying incidental enchondromas, presence of foci with signal similar to bone marrow and foci of signal absence suggestive of calcifications within the enchondromas. Inter-and intraobserver agreements were analyzed. Results: Eleven lesions compatible with enchondromas (3.3%) were identified. The interobserver agreement for the presence of enchondroma was high. Prevalence of foci of bone marrow signal inside the enchondromas was of 54.55%, and foci suggestive of calcification corresponded to 36.36%. The intraobserver agreement for foci of bone marrow signal in enchondromas was perfect, and interobserver agreement was high. Conclusion: The prevalence of incidental enchondromas in the current study was compatible with data in the literature. Excellent agreement was observed in the identification of enchondromas and in the assessment of imaging findings. A higher prevalence of fat signal foci was observed as compared with signal absence suggestive of calcifications. Keywords: Enchondromas; Magnetic resonance imaging; Knee; Bone marrow.Objetivo: Avaliar a confiabilidade intra e interobservador na identificação de encondromas incidentais na ressonância magnética de joelho e estudar a prevalência das características de imagens destas lesões. Materiais e Métodos: Estudo retrospectivo, com revisão de 326 ressonâncias magnéticas do joelho realizadas entre novembro de 2009 e setembro de 2010. As imagens foram analisadas por dois médicos especialistas em radiologia musculoesquelética, de forma independente e às cegas, visando a identificar encondromas incidentais, presença de focos com sinal semelhante à medula óssea e focos de ausência de sinal sugestivos de calcificações no interior dos encondromas. Foram realizadas análises das concordâncias inter e intraobservador. Resultados: Foram identificadas 11 lesões compatíveis com encondromas (3,3%). A concordância interobservador para presença de encondroma foi alta. A prevalência de focos de sinal de medula óssea no interior dos encondromas foi 54,55% e de focos sugestivos de calcificação foi 36,36%. A concordância intraobservador para focos de sinal de medula óssea nos encondromas foi perfeita, e a concordância interobservador foi alta. Conclusão: A prevalência de encondromas incidentais no trabalho atual foi consistente com a literatura. Foi observada excelente concordância no estudo de confiabilidade da identificação de encondromas e de suas características, notando-se maior prevalência de focos com sinal de gordura do que de calcificações. Unitermos: Encondromas; Ressonância magnética; Joelho; Medula óssea. Ab...

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“…Choi et al reported that patients with low-grade CSs had a significantly higher incidence of MR findings including: predominantly intermediate signal on T1-weighted images ( Figure 6A), multilocular appearance on contrast-enhanced T1-weighted images, cortical erosion/destruction, peri-tumoral edema and an involvement of the epiphysis or flat bone. They concluded that MR imaging shows helpful features for differentiating low-grade CS from EC (18). Extensive gadolinium enhancement ( Figure 6B) could also favor the presence of low-grade CS, while peripheral gadolinium enhancement favors EC (19).…”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Long Bone Enchondroma vs. Low-Grade Chondrosarcoma: Current Concepts Review

Jamshidi

Mirzaei

2016

Shafa Ortho J

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Context: Differentiation of low-grade chondrosarcoma (CS) from enchondroma (EC) is a clinical, radiological and pathological challenge. Considering its effect on the choice of therapeutic approach, this paper discusses the distinguishing criteria of low-grade CS and EC. Evidence Acquisition: Evidence of this article came from the result of more than 15500 surgeries of musculoskeletal tumors performed at our center during the previous 26 years, in addition to an inclusive literature review of related published articles. Results: Pain is considered as the most distinguishing clinical criteria of low-grade CS from EC. Aggressive radiologic criteria including cortical destruction, cortical thickening, deep endosteal scalloping and periosteal reaction favor the presence of low-grade CS. Predominantly, intermediate signal on T1-weighted MRI, multilocular appearance on contrast-enhanced T1-weighted MRI, extensive gadolinium enhancement, and peri-tumoral edema could also favor low-grade CS. In addition, permeation of the bone marrow by cartilage and separation of cartilage lobules by fibrous bands could be regarded as the pathologic characteristics of low-grade CS. Conclusions: Radiological evaluation is considered as the first line method in the distinction of low-grade CS and EC. In this regard, attention should be paid to the presence of aggressive radiological features.

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MR differentiation of low-grade chondrosarcoma from enchondroma

Cited by 64 publications

References 21 publications

Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up

Insights into Enchondroma, Enchondromatosis and the risk of secondary Chondrosarcoma. Review of the literature with an emphasis on the clinical behaviour, radiology, malignant transformation and the follow up

Incidental enchondromas at knee magnetic resonance imaging: intraobserver and interobserver agreement and prevalence of imaging findings

Long Bone Enchondroma vs. Low-Grade Chondrosarcoma: Current Concepts Review

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