MR-guided biopsy of suspect breast lesions with a simple stereotaxic add-on-device for surface coils.

Fischer, Uwe; Vosshenrich, R.; Keating, Delia M.; Bruhn, H.; Döler, W.; Oestmann, J W; Grabbe, E

doi:10.1148/radiology.192.1.8208952

Cited by 78 publications

(34 citation statements)

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“…The assessment of enhancing lesions was based on a MRM-BIRADS categorization inaugurated in 1993 and evaluated by Baum et al in 2002 [12]. Whenever MRI of the breasts depicted suspicious lesions that were not visible or reliably reproduced using other imaging modalities (mammography, ultrasound), open biopsies were performed after preoperative MR-guided percutaneous hook-wire localization using a special MR-compatible stereotactic device [13]. All lesions diagnosed as suspicious for malignancy in MRI were removed completely as verified by histopathology.…”

Section: Methods and Patientsmentioning

confidence: 99%

The influence of preoperative MRI of the breasts on recurrence rate in patients with breast cancer

Fischer¹,

Zachariae

Baum³

et al. 2004

Eur Radiol

239

121

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Preoperative MRI of the breasts has been proven to be the most sensitive imaging modality in the detection of multifocal or multicentric tumor manifestations as well as simultaneous contralateral breast cancer. The aim of the presented retrospective study was to evaluate the benefit of preoperative MRI for patients with breast cancer. Preoperative MRI performed in 121 patients (group A) were compared to 225 patients without preoperative MRI (group B). Patients of group A underwent contrast-enhanced MR imaging of the breast using a 2D FLASH sequence technique (TR/TE/FA 336 ms/5 ms/90°; 32 slices of 4-mm thickness, time of acquisition 1:27 min, contrast agent dosage 0.1 mmol Gd-DTPA/kg bw). All patients had histologically verified breast cancer and follow-up for more than 20 months (mean time group A: 40.3 months, group B: 41 months). Both groups received the same types of systemic treatment after breast conserving surgery. The in-breast tumor recurrence rate in group A was 1/86 (1.2%) compared to 9/133 (6.8%) in group B. Contralateral carcinoma were detected within follow-up in 2/121 (1.7%) in group A vs. 9/225 (4%) in group B. All results were statistically significant (P<0.001). Based on these results, preoperative MRI of the breasts is recommended in patients with histopathologically verified breast cancer for local staging.

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Section: Methods and Patientsmentioning

confidence: 99%

The influence of preoperative MRI of the breasts on recurrence rate in patients with breast cancer

Fischer¹,

Zachariae

Baum³

et al. 2004

Eur Radiol

239

121

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show abstract

“…Histopathological assessment can be performed by MRI-guided wire localisation followed by surgical excision [6,9,10], or by alternative techniques to surgery such as MRI-guided percutaneous biopsy using fine needles [11], core needles [12,13] or vacuum-assisted biopsy devices [7,14]. For such a breast intervention to be clinically useful, factors such as safety, accuracy, availability, cost, patient preference for surgical biopsy and surgeon's request should be considered.…”

mentioning

confidence: 99%

Radio-guided occult lesion localisation for breast lesions under computer-aided MRI guidance: the first experience and initial results

Yılmaz

Kılıç²,

Icten³

et al. 2012

BJR

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Objective: The purpose of this study was to present an alternative technique for the pre-operative localisation of solely MRI-detected suspicious breast lesions using a computer-assisted MRI-guided radio-guided occult lesion localisation (ROLL) technique. Methods: Between January 2009 and June 2010, 25 females with a total of 25 suspicious breast lesions that could be detected only by MRI, and for whom breast surgery was planned, underwent the computer-assisted MRI-guided ROLL technique. A seven-channel biopsy breast array coil and computerised diagnostic workstation were used for the localisation procedure. Three-phase dynamic contrast-enhanced axial images were taken. After investigating the localisation co-ordinates with the help of intervention software on a workstation, an 18 G coaxial cannula was placed in the exact position determined. Following verification of the cannula position by additional axial scans, 99m Tc-labelled macroalbumin aggregate and MRI contrast material were injected. Post-procedure MRI scans were used to confirm the correct localisation. Results: All the procedures were technically successful. The mean lesion size was 10.8 mm (range: 4-25 mm). The mean total magnet and the mean localisation times were 28.6 min (range: 18-46 min) and 13.1 min (range: 8-20 min), respectively. Grid and pillar methods were used for localisation in 24 procedures and 1 procedure, respectively. On histopathological examination, 6 malignant, 10 high-risk and 9 benign lesions were identified. All patients tolerated the procedure well. There were no major complications. Conclusion: This is the first report documenting the application of MRI-guided ROLL. Based on our preliminary results, this technique is very efficient and seems to be a good alternative to wire localisation.

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“…By the use of MR, lesions can be identified that are not seen mammographically. But the method of MR-guided needle biopsy of the breast is still too complicated for routine use [31][32][33][34][35]. Although there is the possibility of using ultrasound or MR as guidance modalities for minimally invasive biopsy of DCIS, stereotactic mammography seems to be the best means of targeting suspicious microcalcifications within the breast.…”

Section: Diagnosismentioning

confidence: 99%

Ductal Carcinoma in situ of the Breast: Diagnosis and Management

Friedrich

Felberbaum

Krämer³

et al. 2003

Oncol Res Treat

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Currently, no precise morphologic or biologic prognostic factors reliably identify patients with ductal carcinoma in situ (DCIS) who are at high risk of disease progression. DCIS is a disease with an extremely favorable prognosis and a small likelihood of dying from breast cancer, regardless of what type of treatment is received. No retrospective or prospective study to date has demonstrated a significant difference in breast cancer specific mortality regardless of treatment. The similarities between DCIS and invasive cancer suggest that an important area for future research should be elucidating the processes that can either unleash or contain the invasive potential of DCIS cells. Thus, an understanding of the biology of DCIS can assist in the prevention, the assessment, and the diagnosis of invasive breast cancer.

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MR-guided biopsy of suspect breast lesions with a simple stereotaxic add-on-device for surface coils.

Cited by 78 publications

References 0 publications

The influence of preoperative MRI of the breasts on recurrence rate in patients with breast cancer

The influence of preoperative MRI of the breasts on recurrence rate in patients with breast cancer

Radio-guided occult lesion localisation for breast lesions under computer-aided MRI guidance: the first experience and initial results

Ductal Carcinoma in situ of the Breast: Diagnosis and Management

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