MR imaging of bone marrow lesions: relative conspicuousness on T1-weighted, fat-suppressed T2-weighted, and STIR images.

Mirowitz, Scott A.; Apicella, P; Reinus, William R.; Hammerman, Albert M.

doi:10.2214/ajr.162.1.8273669

Cited by 195 publications

(96 citation statements)

References 9 publications

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“…Selecting the inversion time (TI) such that the longitudinal magnetization of lipid has recovered to zero at the time of echo formation eliminates the signal from fatty tissue, thereby increasing the conspicuity of marrow abnormalities; at 1.5 T, use of a TI in the range of 150-170 ms will achieve this result. STIR is a highly sensitive technique in marrow lesion detection and is considered superior to T1-weighted SE in some studies [21]; however, the findings on STIR images often lack specificity because the STIR sequence suppresses signals from any other tissue that has a T1 relaxation time similar to that of fat. Additionally, in oncologic imaging, STIR may lead to overestimation of the extent of a marrow lesion due to its demonstration of surrounding marrow edema pattern as high signal that may be similar to that of the lesion itself.…”

Section: Fat and Water Contentmentioning

confidence: 99%

Magnetic resonance imaging of bone marrow in oncology, Part 1

Hwang

Panicek

2007

Skeletal Radiol

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Magnetic resonance imaging plays an integral role in the detection and characterization of marrow lesions, planning for biopsy or surgery, and post-treatment followup. To evaluate findings in bone marrow on MR imaging, it is essential to understand the normal composition and distribution of bone marrow and the changes in marrow that occur with age, as well as the basis for the MR signals from marrow and the factors that affect those signals. The normal distribution of red and yellow marrow in the skeleton changes with age in a predictable sequence. Important factors that affect MR signals and allow detection of marrow lesions include alterations in fat-water distribution, destruction of bony trabeculae, and contrast enhancement. This two-part article reviews and illustrates these issues, with an emphasis on the practical application of MR imaging to facilitate differentiation of normal marrow, tumor, and treatment-related marrow changes in oncology patients.

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Section: Fat and Water Contentmentioning

confidence: 99%

Magnetic resonance imaging of bone marrow in oncology, Part 1

Hwang

Panicek

2007

Skeletal Radiol

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“…Fatty marrow appears hyperintense on T1-weighted sequences since lipid protons have short T1 relaxation times. Red marrow contains more water and has an intermediate T1 relaxation time, and appears to have a lower signal than subcutaneous fat, but a higher one than intervertebral discs or muscles (15,16). The physiological reconversion and pathological situations may easily be followed with MR imaging.…”

Section: Discussionmentioning

confidence: 99%

Sigara kullanımı ve hemoglobin değerlerinin femur kemik iliği manyetik rezonans intensitesi üzerine etkisi

Arslan¹,

Şanel²,

Çubuk³

et al. 2017

Bakirkoy

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“…STIR images characterize the yellow marrow as SI being nullified and therefore appearing black. The T1 and T2 contrast of tissues other than fat is additive, and contrast sensitivity is thus greatly enhanced (3,17,18). Because the fat signal is highlighted on T1WI, whereas the cellular portion is emphasized on STIR images, one (patient No.…”

Section: Discussionmentioning

confidence: 99%

Magnetic Resonance Imaging of the Bone Marrow After Bone Marrow Transplantation or Immunosuppressive Therapy in Aplastic Anemia

et al. 2001

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To compare magnetic resonance (MR) images of the bone marrow (BM) after bone marrow transplantation or immunosuppressive therapy in patients with aplastic anemia (AA), MR imaging of BM was reviewed retrospectively in 16 patients (13 males and 3 females, mean age 26 yr) with AA who completely responded clinically after transplantation or immunosuppressive therapy. The signal intensity (SI) of BM was classified into four patterns according to the increasing amount of cellular marrow, i.e., pattern I to IV. SI of MR imaging of BM exhibited an increase of cellular marrows following both transplantation and immunosuppressive therapy. Of the eight patients on transplantation, the SI of the lumbar spinal BM was pattern III in two patients and IV in six on T1-weighted and short tau inversion recovery (STIR) images. In the eight patients with immunosuppressive therapy, the SI of the lumbar spinal BM was pattern II in one, III in five, and IV in two on T1-weighted images and pattern II in one, III in four, and IV in three on STIR images. SI on MR imaging of the lumbar spinal BM showed a more cellular pattern in patients on transplantation than in those on immunosuppressive therapy.

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MR imaging of bone marrow lesions: relative conspicuousness on T1-weighted, fat-suppressed T2-weighted, and STIR images.

Cited by 195 publications

References 9 publications

Magnetic resonance imaging of bone marrow in oncology, Part 1

Magnetic resonance imaging of bone marrow in oncology, Part 1

Sigara kullanımı ve hemoglobin değerlerinin femur kemik iliği manyetik rezonans intensitesi üzerine etkisi

Magnetic Resonance Imaging of the Bone Marrow After Bone Marrow Transplantation or Immunosuppressive Therapy in Aplastic Anemia

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