MR imaging of fetal cerebral anomalies

Sonigo, P.; Rypens, Françoise; Carteret, Michel; Delezoide, Anne‐Lise; Brunelle, Françis

doi:10.1007/s002470050335

Cited by 196 publications

(134 citation statements)

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“…20 Posterior fossa abnormalities were also a common additional finding, which has been observed in other studies of prenatally diagnosed ACC with fetal and/or postnatal MR imaging. 4,10,11,[28][29][30] Interestingly, cerebellar hemispheric abnormalities were more common than vermian abnormalities in our study, a finding that is similar to those in other prenatal MR imaging studies 4,10 but different from those in postnatal MR imaging studies, 20,31 perhaps due to the difficulty in evaluating the fetal vermis or due to termination of those cases with prenatally diagnosed cerebellar abnormalities. Brain stem abnormalities were also common, occurring in 33% of patients in our study.…”

Section: Discussionsupporting

confidence: 80%

“…4,5,10,11,28,29 In addition, fetal MR imaging identified abnormalities not detected by prenatal sonography in most (83%) patients; this difference is in agreement with prior studies and further supports the need for fetal MR imaging in cases of sonographically suspected ACC. 5,28,30,32,33 In most fetuses, the additional abnormalities were suggestive of a developmental etiology. In 5 fetuses (17%), there were extensive additional malformations identified by fetal MR imaging and suggestive of a genetic syndrome.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Agenesis of the Corpus Callosum: An MR Imaging Analysis of Associated Abnormalities in the Fetus

Tang¹,

Bartha²,

Norton³

et al. 2008

AJNR Am J Neuroradiol

131

102

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BACKGROUND AND PURPOSE:Anomalies associated with callosal agenesis (ACC) found postnatally have been well documented. However, to our knowledge, no detailed MR imaging analysis of associated anomalies has been reported in a large cohort of fetuses with ACC. This study will assess those anomalies and compare them with postnatal cohorts of ACC, to identify associated fetal brain abnormalities that may give insight into etiology and outcome.

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 99%

Agenesis of the Corpus Callosum: An MR Imaging Analysis of Associated Abnormalities in the Fetus

Tang¹,

Bartha²,

Norton³

et al. 2008

AJNR Am J Neuroradiol

131

102

View full text Add to dashboard Cite

show abstract

“…One area in which MRI has proven to be especially beneficial is in evaluation of the fetal CNS (61)(62)(63)(64)(65)(66)(67). Sonographic evaluation of the fetal CNS is limited by: 1) the nonspecific appearance of some anomalies; 2) technical factors that limit resolution of the side of the brain near the transducer; 3) ossification, which obscures visualization of posterior fossa structures; and 4) subtle parenchymal abnormalities that frequently cannot be visualized with ultrasound (68).…”

Section: Cns Anomaliesmentioning

confidence: 99%

“…Due to shared placental vasculature, when one twin dies there is often ischemic damage to the surviving monochorionic twin. Parenchymal damage is visualized as focal or diffuse areas of increased T 2 signal (62,73). Later findings include porencephaly, and decreased parenchymal volume (74).…”

Section: Cns Anomaliesmentioning

confidence: 99%

Obstetric MRI

Levine

2006

Magnetic Resonance Imaging

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Ultrasound is the imaging modality of choice for pregnant patients. However, MRI is increasingly utilized in patients in whom the sonographic diagnosis is unclear. These include maternal conditions unique to pregnancy such as ectopic pregnancy, placenta accreta, and uterine dehiscence. MRI is also being increasingly utilized in the assessment of abdominopelvic pain in pregnancy, in particular in assessment for appendicitis. Fetal MRI is performed to assess central nervous system (CNS) abnormalities and patients who are considering fetal surgery for conditions such as neural tube defects, congenital diaphragmatic hernia, and masses that obstruct the airway. In the future, functional MRI and fetal volumetry may provide additional information that can aid in our care of complicated pregnancies.

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“…Due to its better contrast and temporal resolution MR imaging can detect cortical malformations that were not identified on US. The results of one study showed that MRI is superior in identifying schizencephaly, lissencephaly, polymicrogyria, and gray matter heterotopia in fetuses (44). It is important to be familiar with the normal appearance of fetal brain at different gestational ages to be able to identify these malformations.…”

Section: Malformations Of Cortical Developmentmentioning

confidence: 99%

A peek into the uterus – MRI of the fetal CNS

Vesnaver

2016

Pedaiatr Today

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The purpose of this article is to provide an overview of MR imaging of the fetal central nervous system, and to briefly discuss recent advances. Fetal MRI has been commonly used throughout the world for over 20 years. Compared to US it has better contrast resolution, allows direct visualization of both hemispheres and the additional limitations of sonography do not affect the quality of MRI. There are no known adverse short-term or long-term side effects of MRI in children, who were imaged in the fetal period. The standard protocol for fetal MRI consists of single-shot rapid acquisition T2 weighted sequences in three planes, fast spoiled gradient recalled T1 weighted sequence, T2 gradient echo sequence and diffusion weighted sequence in the axial plane. The clinical applications of advanced MRI techniques are still limited. Fetal MRI is performed to confirm abnormalities detected on US, and to exclude additional pathology. Interpreting fetal MRI images requires understanding of normal fetal CNS development and one should also evaluate other fetal structures, the umbilical cord and placenta. The most common indication for MR imaging of the fetal CNS is mild ventriculomegaly. Other common indications, that are also discussed in the article, include commissural abnormalities, infratentorial abnormalities, cortical malformations, spinal pathology and complications of monochorionic twin pregnancy. ConclusionFetal MRI provides important information in prenatal counseling, therefore familiarity with the applications and limitations of fetal MRI, and multidisciplinary collaboration remain essential for the radiologist involved in prenatal imaging.

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MR imaging of fetal cerebral anomalies

Cited by 196 publications

References 0 publications

Agenesis of the Corpus Callosum: An MR Imaging Analysis of Associated Abnormalities in the Fetus

Agenesis of the Corpus Callosum: An MR Imaging Analysis of Associated Abnormalities in the Fetus

Obstetric MRI

A peek into the uterus – MRI of the fetal CNS

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