MR Imaging of Fetal Sacrococcygeal Teratoma

Abstract

Sacrococcygeal teratomas had characteristic MR imaging appearances that allowed a complete assessment in most fetuses. Because of MR imaging, the prenatal evaluation was changed in some patients and affected counseling of the parents and treatment. MR imaging is a valuable adjunct to obstetric sonography for the prenatal evaluation of sacrococcygeal teratoma.

Obstetric MRI

“…MR imaging allows for better evaluation of the intrapelvic extension than does ultrasound (99 -101). In addition, MR imaging can illustrate intraspinal extent, which is occult by sonography (101). This information is important, since it will affect the postnatal surgical approach to the lesion (101).…”

“…This information is important, since it will affect the postnatal surgical approach to the lesion (101). Fetal MR imaging has been shown to be useful for planning postpartum surgery (86,97,99,101), and for decision-making regarding the timing and mode of delivery (101).…”

Osteosarcoma Cells Differentiate into Phenotypes from all Three Dermal Layers

“…Primary antibodies for phenotypes obtained from Sigma-Aldrich were: muscle-type intermediate filaments with monoclonal anti-desmin clone De-U-10 at 1:400 [13], oligodendrocytes or myelin with monoclonal anti-CNPase [1,44], monoclonal antibody VM-1 for keratinocytes at 1:200, monoclonal antibody for glial fibrillary acidic protein (GFAP) for astrocytes at 1:400, and smooth muscle a-actin (IA4) (Sigma-Aldrich) at 1:400. Primary antibodies for phenotypes obtained from the Developmental Hybridoma Bank were: striated muscle with antibody to heavy chain of myosin (MF-20), cartilage with Type II collagen (CIICI), bone with bone sialoproteins I and II (WVIDI 9C5), osteonectin (MPIIIB10 1 ), P2A4 and P2B1 for endothelial cells.…”

Fetal magnetic resonance imaging in obstetric practice

“…MRI is highly effective in demonstrating cardiac rhabdomyomas and subependymal tubers before week 21. The differentiation of tubers from hamartomas and subcortical heterotopic brain tissue can be made (49 (50). In Figure 2 (a, b), a 14x11x11 cm sized sacrococcygeal teratoma filling the whole fetal pelvis showing exophytic extensions to the pelvic and anal regions is seen.…”