MR imaging of hepatic adenoma.

Gabata, Toshifumi; Matsui, Osamu; Kadoya, Masumi; Takashima, Tsutomu; Ueda, Yoshihiro; Komatsu, Yoji; Sasaki, Michihito

doi:10.2214/ajr.155.5.2120926

Cited by 25 publications

(7 citation statements)

References 4 publications

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“…Galata et al (24) found that HCC, alongwith other malignant tumors such as metastases, can often be distinguished from benign lesions containing normal hepatocytes (eg, FNH or adenomas), because the malignant lesions have a higher signal intensity on T2-weighted images. T2-weighted sequences may also be used to distinguish HCC from hemangiomas, since hemangiomas have very high signal intensity and a great lesion-liver signal intensity difference with these sequences ( 12).…”

Section: Fnhmentioning

confidence: 99%

Mn‐DPDP enhancement patterns of hepatocellular lesions on MR images

Vogl¹,

Hamm²,

Schnell³

et al. 1993

Magnetic Resonance Imaging

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The recently developed paramagnetic hepatobiliary contrast agent manganese dipyridoxyl diphosphate (DPDP) was evaluated in eight patients. Pathologic diagnoses included five hepatocellular carcinomas, two cirrhoses, and one focal nodular hyperplasia. T1-weighted spin-echo and gradient-echo images were obtained after intravenous injection of 5 or 10 mumol/kg Mn-DPDP; these were compared with unenhanced T1-weighted spin-echo and gradient-echo images and T2-weighted spin-echo images. In all patients with lesions of hepatocellular origin, focal areas of increased enhancement were seen in the lesions after administration of Mn-DPDP. In the cirrhotic livers, these areas corresponded to foci of hepatic regeneration. In all patients, the signal-to-noise ratio in normal liver tissue increased significantly after injection of Mn-DPDP. Signal intensity in the six primary liver tumors was further increased, so that they appeared hyperintense relative to surrounding liver tissue on all T1-weighted images. Conspicuity and demarcation of all lesions were improved on Mn-DPDP-enhanced images.

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Section: Fnhmentioning

confidence: 99%

Mn‐DPDP enhancement patterns of hepatocellular lesions on MR images

Vogl¹,

Hamm²,

Schnell³

et al. 1993

Magnetic Resonance Imaging

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“…HCCs usually show low density (or intensity) on contrast-enhanced images obtained over 2 min after the administration of contrast material [2], HCCs are demonstrated as tumors with neovascularity and tumor stain on hepatic arteriography. On CTAP almost all HCCs are shown as Filling defects since they receive little blood supply from the portal 26 Ohtomo/Itai I maging of Hepatocellular Carcinoma nuaied area (arrowhead). Ii is seen as an ¡soattcnuatedareaon plain CT (not shown) and no tumor stain is noted on the early phase of dynamic CT (not shown), e Enhancement is seen within the mass in the poste rior segment on CTAP.…”

Section: Contrast Studymentioning

confidence: 99%

“…The differential diagnosis between well-differentiated HCC and hepatic adenoma is difficult, both radiologically and pathologically. MR imaging might be useful in this differentiation since an encapsulated large hepatic adenoma has been reported to be isointense on T2-weighted images [26].…”

Section: Hepatic Adenomamentioning

confidence: 99%

Imaging of Hepatocellular Carcinoma

Ohtomo

Itai

1995

Dig Surg

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We reviewed recent advances in the imaging of hepatocellular carcinoma (HCC), with particular emphasis on the early detection of small nodular HCC. In high-risk patients, periodic ultrasound screening with tumor marker (α-fetoprotein and PIVKA-11) measurement is the most useful method to detect small HCC. Computed tomography (CT) is the second choice, and an incremental dynamic technique using spiral CT is useful in the detection and differentiation. Magnetic resonance (MR) imaging is used to differentiate HCC from cavernous hemangioma and some tumor-like conditions including adenomatous hyperplasia. In selected patients, CT during arterial portography and superparamagnetic iron oxide-enhanced MR imaging are diagnostic. Characteristic findings of HCC are a peritumoral fibrous capsule, an intratumoral mosaic appearance and hypervascularity; however, these findings are not frequently seen in HCC < 2 cm. Imaging characteristics of some variants of HCC and the differentiation of HCC from other hepatic tumors and tumorlike conditions are also discussed.

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“…The relation between oral contraceptives and liver cell adenoma is well established [1,2]. The regression of adenoma after withdrawal of oral contraceptives has been documented in a few cases mostly by means of liver scans or angiograms, and sonography [3][4][5][6][7][8].The appearance of liver cell adenoma at computed tomography (CT) and magnetic resonance (MR) imaging is well documented [9][10][11][12][13][14][15][16][17][18]. To our knowledge, though, there are no reports of CT scanning or MR imaging for monitoring the regression of a liver cell adenoma.…”

mentioning

confidence: 99%

“…The appearance of liver cell adenoma at computed tomography (CT) and magnetic resonance (MR) imaging is well documented [9][10][11][12][13][14][15][16][17][18]. To our knowledge, though, there are no reports of CT scanning or MR imaging for monitoring the regression of a liver cell adenoma.…”

mentioning

confidence: 99%

Disappearance of liver cell adenoma: CT and MR imaging

et al. 1997

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We report the disappearance of liver cell adenoma, documented by computed tomography (CT) and magnetic resonance (MR) imaging. A 42-year-old woman with a diagnosis of hepatic adenoma was followed up by CT and MR imaging after cessation of oral contraceptive use. At the time of diagnosis, the adenoma was 4 cm in diameter and appeared hypervascular on CT. At MR imaging, the lesion was hypointense on T1-weighted sequences, and hyperintense on T2-weighted sequences. The lesion disappeared 4 years after cessation of oral contraceptive use. We conclude that in nonoperated patients CT scans and MR imaging are useful for following the evolution, and documenting the regression, of liver cell adenomas.

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MR imaging of hepatic adenoma.

Cited by 25 publications

References 4 publications

Mn‐DPDP enhancement patterns of hepatocellular lesions on MR images

Mn‐DPDP enhancement patterns of hepatocellular lesions on MR images

Imaging of Hepatocellular Carcinoma

Disappearance of liver cell adenoma: CT and MR imaging

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