MR Imaging of Lymphomas

Initial experience with FSE STIR whole-body MR imaging for staging lymphoma in children

“…Furthermore, complete assessment of the disease burden appears possible with one single imaging study, resulting in savings in cost, sedations and number of patient visits. The rationale for utilizing FSE STIR sequences for whole-body MR imaging of lymphoma was that regional STIR imaging has been shown to detect lymphomatous involvement of bone marrow [10,14,15,17,31] and lymph nodes [14,16,17] based on its combined T1 and T2 contrast with inherent saturation of signal from fat. We also expected that FSE STIR imaging would show lymphomatous involvement of parenchymal organs.…”

“…Accurate determination of disease extent by imaging is an essential part of staging childhood lymphoma. A wide volvement of lymph nodes [13][14][15][16][17][18] and parenchymal organs [14,15,18], it has not been used routinely for staging the entire body, due in part to the lengthy examination times required when utilizing conventional spinecho sequences.…”

Mr Imaging of Pediatric Hematologic Disorders

“…Lymphoma, like metastases, commonly spreads as focal nodules of tumor (5). Malignant tumors are often inhomogeneous with mixed signal intensity on TI-and T2-weighted images (4) and can show a decreased signal on Tl-weighted images (3).…”

“…MR imaging can assess the extent of involvement (Figs I and 10) and is also effective in assessing the efficiency of chemotherapy and/or irradiation (Fig. 3) (3)(4)(5). While MR is sensitive in detecting tumor spread, specificity in diagnosis is often questionable, necessitating biopsy or other forms of correlation (4).…”

MR Imaging of Pediatric Hematologic Disorders

“…Lymphoma, like metastases, commonly spreads as focal nodules of tumor (5). Lymphoma, like metastases, commonly spreads as focal nodules of tumor (5).…”