MR Imaging of Soft-Tissue Masses of the Foot

Gentili, Amilcare; Sorenson, Steven; Masih, Sulabha

doi:10.1055/s-2002-32360

Cited by 16 publications

(10 citation statements)

References 42 publications

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“…The spatial resolution afforded by MRI also allows the identification of subclinical tophaceous deposits, with some lesions demonstrable prior to radiographic detection (8,17). MRI of the extremities may also be useful in differentiating gouty tophi from infectious or neoplastic lesions and, as such, may assist in planning additional diagnostic and management strategies (13,14,16,18). In the present study, MRI was found to provide an acceptable means of determining tophus volume.…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging in the quantitative assessment of gouty tophi

Schumacher

Becker

Edwards

et al. 2006

International Journal of Clinical Practice

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Measurements of tophus size can be important in monitoring the course of gout therapy, as tophus resolution is proposed as one measure of success of treatment. This multicentre study assessed the intra-and interreader reproducibility of quantitative tophus volume measurements from magnetic resonance images (MRI) in subjects with palpable gouty tophi. Subjects first underwent radiographic imaging of a selected tophus followed by MRI before and at 5, 10 and 20-min after gadolinium administration. After choosing optimal parameters, subjects underwent pre-and postgadolinium-enhanced MRIs of a selected tophus on two occasions separated by 5-10 days. Unenhanced spin-echo images provided satisfactory tophi images and were less subject to interfering artefacts than gadolinium-enhanced gradient-echo images. Intrareader reproducibility was excellent, with no statistically significant difference in mean tophus volume between visits (mean difference À 0.05 AE 0.97 cm 3 ). A small but statistically significant difference in interreader mean tophus volume was detected (mean difference 0.89 AE 2.05 cm 3 ; p < 0.05). MRI can quantify tophus size in gout and deserves further comparison with other techniques for tophus size monitoring in assessing effects of gout therapy.

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Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging in the quantitative assessment of gouty tophi

Schumacher

Becker

Edwards

et al. 2006

International Journal of Clinical Practice

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“…In our study, the absence of high T2 signal or marked contrast enhancement argues strongly against synovial sarcoma, the most common malignant tumor of the foot and ankle [9], [10]. Clear-cell carcinoma, a slow growing malignancy with a predilection for the lower extremities in younger adults is also unlikely in view of the absence of either hyperintensity on T1-weighted images or an aggressive growth pattern [6], [9].…”

Section: Discussionmentioning

confidence: 81%

The magnetic resonance appearance of surfers' knots: a case report

McManus

Thomson

Whan

2016

Radiology Case Reports

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Athletes are at increased risk of developing soft-tissue lesions of the lower limbs. Although the majority of these will be benign, the differential diagnosis is broad and increasingly, doctors are turning to magnetic resonance imaging (MRI) as a first-line investigation when presented with these sorts of lesions, both to narrow the differential diagnosis and exclude malignancy. We report the case of a 28-year-old Caucasian man who presented with 2 soft-tissue lesions of the right foot. History and examination of the nodules fitted with a diagnosis of surfers' knots, an unusual form of acquired, benign, connective tissue nodule that may appear over the tibial tuberosities, dorsum of the feet, and occasionally on the chest of surfers in association with repetitive microtrauma during surfing. MRI findings were consistent with this diagnosis with both lesions exhibiting T1 hypointensity and speckled T2 hypointensity with no significant blooming artifact on gradient echo imaging. When imaged with gadolinium, they demonstrated only mild contrast enhancement. MRI is a valuable tool when investigating athletes with soft-tissue lesions over the lower limbs where the possibility of malignancy must be addressed. In selected cases, MRI may be sufficient to permit a conservative approach to the management of these patients.

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“…Though ultrasound has some utility, MRI is considered the provisional gold standard for diagnosis, given its ability to discern soft tissue by signal intensity [3,6]. In this case, minimal contrast (gadolinium) uptake, in addition to enhanced signal in T1-weighted images and margin preservation, was characteristic of muscle hypertrophy [3].…”

Section: Discussionmentioning

confidence: 99%