MR-Tomographie und -Spektroskopie der Skelettmuskulatur bei hohen Magnetfeldstärken

Abstract

Intact as well as neuromuscular affected skeletal muscles can be precisely analysed by MR tomography with high magnetic field strengths. The substitution of muscle by adipose tissue under atrophic conditions is seen most clearly in fat images, while the morphology of small structures is predominantly shown by water images. The aim of in-vivo spectroscopy is an identification and quantification of metabolites. A relative increase in the amount of adipose tissue within atrophic muscles was confirmed by the 1-H spectrum. As concluded from 13-C and 31-P spectra there was neither a change in adipose tissue composition nor a modification of energy metabolism.

Magnetic resonance imaging in skeletal muscle following denervation and electrical stimulation

“…In this investigation, it has been necessary to evaluate very small ROIs, because within the anyway small objects of FDS and TA muscles, areas of fascia and fat had to be excluded. However, this has been possible without prob lems because of the high resolution of MRI, which is said to be less than 1 mm [23]. The good reproducibility is shown by the low stan dard deviation of normal values, which already has been found in a previous investigation [17].…”